ArticleJournal of cardiothoracic and vascular anesthesia2021
Nitric Oxide Ventilation Improves Recirculation and Right Ventricular Function During Veno-Venous Extracorporeal Membrane Oxygenation in a COVID-19 Patient.
Article in Journal of cardiothoracic and vascular anesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Unraveling the impact of nitric oxide, almitrine, and their combination in COVID-19 (at the edge of sepsis) patients: a systematic review.Frontiers in pharmacology · 2023Pooled it
- Cannula tip separation and configuration as determinants of recirculation in venovenous ECMO.The journal of extra-corporeal technology · 2026Article
- Successful management of severeFrontiers in medicine · 2026Article
- Case Report: Successful repair of traumatic right main bronchial transection under veno-venous ECMO support with postoperative inhaled nitric oxide.Frontiers in medicine · 2026Article
- Right-sided heart failure in acute respiratory distress syndrome.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Recirculation in Veno-Venous Extracorporeal Membrane Oxygenation.Medicina (Kaunas, Lithuania) · 2024Review
- Right ventricular injury in patients with COVID-19-related ARDS eligible for ECMO support: a multicenter retrospective study.Annals of intensive care · 2024Article
- The Potential Role of Nitric Oxide as a Therapeutic Agent against SARS-CoV-2 Infection.International journal of molecular sciences · 2023Review
- Utility of NO and HNitric oxide : biology and chemistry · 2022Review
- More questions than answers for the use of inhaled nitric oxide in COVID-19.Nitric oxide : biology and chemistry · 2022Review
- Protecting the Injured Right Ventricle in COVID-19 Acute Respiratory Distress Syndrome: Can Clinicians Personalize Interventions and Reduce Mortality?Journal of cardiothoracic and vascular anesthesia · 2021Article
- EACTA/SCA Recommendations for the Cardiac Anesthesia Management of Patients With Suspected or Confirmed COVID-19 Infection: An Expert Consensus From the European Association of Cardiothoracic Anesthesiology and Society of Cardiovascular Anesthesiologists With Endorsement From the Chinese Society of Cardiothoracic and Vascular Anesthesiology.Journal of cardiothoracic and vascular anesthesia · 2021Article
- The Right Ventricle in COVID-19 Lung Injury: Proposed Mechanisms, Management, and Research Gaps.Journal of cardiothoracic and vascular anesthesia · 2021Article
- Saying no to SARS-CoV-2: the potential of nitric oxide in the treatment of COVID-19 pneumonia.Medical gas researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with coronavirus disease 2019 (COVID-19) are prone to pulmonary artery hypertension (PAH) and right ventricular pressure overload due to severe bilateral infiltrates, high ventilation pressures, persistent hypoxemia, pulmonary fibrosis, and/or pulmonary embolism. In patients on extracorporeal membrane oxygenation (ECMO), this potentially leads to increased recirculation. In the current report, the authors present a case in which continuous inhaled nitric oxide (iNO)-enriched ventilation was effective in terms of PAH and recirculation reduction in a COVID-19 patient on veno-venous ECMO.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.