Evidence map›Paper›PMID 33077126›Full record

ArticleJournal of thermal biology2020

Echocardiographic changes following active heat acclimation.

Iain T Parsons, Daniel Snape, John O'Hara, David A Holdsworth, Michael J Stacey, Nick Gall, Phil Chowienczyk, Barney Wainwright, David R Woods

Open access · greenAbstract read
In one paragraph

Article in Journal of thermal biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Iain T ParsonsResearch and Clinical Innovation, Royal Centre for Defence Medicine, Birmingham, UK; School of Cardiovascular Medicine and Sciences, King's College London, UK. Electronic address: iain.parsons@kcl.ac.uk.
Daniel SnapeResearch Institute for Sport, Physical Activity and Leisure, Carnegie School of Sport, Leeds Beckett University, UK. Electronic address: d.snape@leedsbeckett.ac.uk.
John O'HaraResearch Institute for Sport, Physical Activity and Leisure, Carnegie School of Sport, Leeds Beckett University, UK. Electronic address: j.ohara@leedsbeckett.ac.uk.
David A HoldsworthResearch and Clinical Innovation, Royal Centre for Defence Medicine, Birmingham, UK. Electronic address: david.holdsworth@nhs.net.
Michael J StaceyResearch and Clinical Innovation, Royal Centre for Defence Medicine, Birmingham, UK. Electronic address: michael.stacey@nhs.net.
Nick GallSchool of Cardiovascular Medicine and Sciences, King's College London, UK. Electronic address: nicholasgall@nhs.net.
Phil ChowienczykSchool of Cardiovascular Medicine and Sciences, King's College London, UK. Electronic address: phil.chowienczyk@kcl.ac.uk.
Barney WainwrightResearch Institute for Sport, Physical Activity and Leisure, Carnegie School of Sport, Leeds Beckett University, UK. Electronic address: barney.wainwright@leedsbeckett.ac.uk.
David R WoodsResearch and Clinical Innovation, Royal Centre for Defence Medicine, Birmingham, UK; Research Institute for Sport, Physical Activity and Leisure, Carnegie School of Sport, Leeds Beckett University, UK. Electronic address: DoctorDRWoods@aol.com.
King's College London · GBLeeds Beckett University · GBRoyal Navy · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heat adaption through acclimatisation or acclimation improves cardiovascular stability by maintaining cardiac output due to compensatory increases in stroke volume. The main aim of this study was to assess whether 2D transthoracic echocardiography (TTE) could be used to confirm differences in resting echocardiographic parameters, before and after active heat acclimation (HA). Thirteen male endurance trained cyclists underwent a resting blinded TTE before and after randomisation to either 5 consecutive daily exertional heat exposures of controlled hyperthermia at 32°C with 70% relative humidity (RH) (HOT) or 5-days of exercise in temperate (21°C with 36% RH) environmental conditions (TEMP). Measures of HA included heart rate, gastrointestinal temperature, skin temperature, sweat loss, total non-urinary fluid loss (TNUFL), plasma volume and participant's ratings of perceived exertion (RPE). Following HA, the HOT group demonstrated increased sweat loss (p = 0.01) and TNUFL (p = 0.01) in comparison to the TEMP group with a significantly decreased RPE (p = 0.01). On TTE, post exposure, there was a significant comparative increase in the HOT group in left ventricular end diastolic volume (p = 0.029), SV (p = 0.009), left atrial volume (p = 0.005), inferior vena cava diameter (p = 0.041), and a significant difference in mean peak diastolic mitral annular velocity (e') (p = 0.044). Cardiovascular adaptations to HA appear to be predominantly mediated by improvements in increased preload and ventricular compliance. TTE is a useful tool to demonstrate and quantify cardiac HA.

Indexed as

ExerciseSweatingThermotoleranceAdultEchocardiographyHeartHeart RateHumansMalePlasma VolumeRandom AllocationVasodilationDiastolic functionEchocardiographyHeat acclimationHeat adaptationPlasma volumePreloadStroke volume

Identifiers

PMID33077126
PMCPMC7467033
OpenAlexW3081650630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.