SynthesisCritical care (London, England)2020
Sex differences in survival after out-of-hospital cardiac arrest: a meta-analysis.
Synthesis in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 87 citations in OpenAlex.
- Advanced Prehospital Airway Management: Analyzing Success Rates and Predictors of King Laryngeal Tube Use.Healthcare (Basel, Switzerland) · 2026Article
- Equal cardiac arrest care - a qualitative study of healthcare professionals' experiences.BMC medical ethics · 2026Article
- Underuse of bystander defibrillation on females during out-of-hospital cardiac arrest: a retrospective observational study in Aotearoa New Zealand.Resuscitation plus · 2026Article
- Vascular access in out-of-hospital cardiac arrest with non-shockable rhythms-a retrospective observational study of the intravenous versus intraosseous approach: the VANISH study.Frontiers in public health · 2026Observational
- Article
- Association Between the Duration of Elevated Perfusion Pressure and Neurological Outcomes in Out-of-Hospital Cardiac Arrest Survivors.Reviews in cardiovascular medicine · 2025Article
- Sex-Specific Outcome Following Targeted Blood Pressure, Oxygenation, and Fever Control After Out-of-Hospital Cardiac Arrest.JACC. Advances · 2025Article
- Psychometric evaluation of EQ-5D-5L in OHCA survivors from the TTM2 trial: aResuscitation plus · 2025Article
- Sex disparities in ICU care and outcomes after cardiac arrest: a Swiss nationwide analysis.Critical care (London, England) · 2025Article
- Sex differences and gender-oriented characteristics in intensive care unit admissions for patients with traumatic brain injury in Spain.Frontiers in medicine · 2025Article
- Long-term neurological outcome following out-of-hospital cardiac arrest in Switzerland: a single-centre observational study.Frontiers in medicine · 2025Article
- CPR training as a gender and rights-based healthcare issue.Health promotion international · 2024Observational
- Sex differences in extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: nationwide multicenter retrospective study in Japan.Critical care (London, England) · 2024Article
- Sex and 30-day survival following out-of-hospital cardiac arrest in Scotland 2011-2020.International journal of emergency medicine · 2024Article
- Global Sex Disparities in Bystander Cardiopulmonary Resuscitation After Out-of-Hospital Cardiac Arrest: A Scoping Review.Journal of the American Heart Association · 2024Article
- Incidence, characteristics, and prehospital outcomes of out-of-hospital cardiac arrest in Qatar: a nationwide gender-based investigation.International journal of emergency medicine · 2024Article
- Long-Term Socioeconomic and Mental Health Changes After Out-of-Hospital Cardiac Arrest in Women and Men.Circulation. Cardiovascular quality and outcomes · 2024Article
- Variable importance analysis with interpretable machine learning for fair risk prediction.PLOS digital health · 2024Article
- Impact of sex of bystanders who perform cardiopulmonary resuscitation on return of spontaneous circulation in out-of-hospital cardiac arrest patients: A retrospective, observational study.Resuscitation plus · 2024Article
- Impact of Preexisting Depression and Anxiety on Hospital Readmission and Long-Term Survival After Cardiac Arrest.Journal of intensive care medicine · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOut-of-hospital cardiac arrest (OHCA) is a leading cause of sudden cardiac death worldwide. Researchers have found significant pathophysiological differences between females and males and clinically significant sex differences related to medical services. However, conflicting results exist and there is no uniform agreement regarding sex differences in survival and prognosis after OHCA. Therefore, we investigated the relationship between the prognosis of OHCA and sex factors.
methodsWe comprehensively searched the PubMed, Embase, and Cochrane databases and obtained a total of 1042 articles, from which 33 studies were selected for inclusion. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a random-effects model.
resultsThe meta-analysis included 1,268,664 patients. Compared with males, females were older (69.7 years vs. 65.4 years, p < 0.05) and more frequently suffered OHCA without witnesses (58.39% vs 62.70%, p < 0.05). Females were less likely to receive in-hospital interventions than males. There was no significant difference between females and males in the survival from OHCA to hospital admission (OR 0.99, 95% CI 0.89-1.1). However, females had lower chances for survival from hospital admission to discharge (OR 0.59, 95% CI 0.48-0.73), overall survival to hospital discharge (OR 0.73, 95% CI 0.62-0.86), and favorable neurological outcomes (OR 0.62, 95% CI 0.47-0.83) compared with males.
conclusionsOur results indicate that the overall discharge survival rate of females is lower than that of males, and females face a poor prognosis of the nervous system. This is likely related to the pathophysiological characteristics of females, more conservative treatment measures compared with males, and different post-resuscitation care. However, these findings should be interpreted with caution due to the presence of several confounding factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.