Evidence map›Paper›PMID 33076873›Full record

ArticleBMC ophthalmology2020

Characteristics and outcomes of vitrectomy for proliferative diabetic retinopathy in young versus senior patients.

Mengyu Liao, Xiaohong Wang, Jinguo Yu, Xiangda Meng, Yuanyuan Liu, Xue Dong, Jianan Li, Rodrigo Brant, Bo Huang, Hua Yan

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Predictors of vision-threatening proliferative diabetic retinopathy in the fellow eye after unilateral vitrectomy: a clinical and imaging-based study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  6. Bilateral vitrectomy in patients with proliferative diabetic retinopathy-characteristics and surgical outcomes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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  8. Refining vitrectomy for proliferative diabetic retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Mengyu LiaoDepartment of Ophthalmology, Tianjin Medical University General Hospital, No.154 Anshan Road, Tianjin, 300052, China.
Xiaohong WangLaboratory of Molecular Ophthalmology, Tianjin Medical University, Tianjin, China.
Jinguo YuDepartment of Ophthalmology, Tianjin Medical University General Hospital, No.154 Anshan Road, Tianjin, 300052, China.
Xiangda MengDepartment of Ophthalmology, Tianjin Medical University General Hospital, No.154 Anshan Road, Tianjin, 300052, China.
Yuanyuan LiuDepartment of Ophthalmology, Tianjin Medical University General Hospital, No.154 Anshan Road, Tianjin, 300052, China.
Xue DongLaboratory of Molecular Ophthalmology, Tianjin Medical University, Tianjin, China.
Jianan LiDepartment of Ophthalmology, Tianjin Medical University General Hospital, No.154 Anshan Road, Tianjin, 300052, China.
Rodrigo BrantDepartment of Ophthalmology and Visual Sciences, Federal University of São Paulo, São Paulo, Brazil.
Bo HuangDepartment of Ophthalmology, University of Mississippi Medical Center, Jackson, USA.
Hua YanDepartment of Ophthalmology, Tianjin Medical University General Hospital, No.154 Anshan Road, Tianjin, 300052, China. phuayan2000@163.com.ORCID http://orcid.org/0000-0001-9115-490X
Tianjin Medical University General Hospital · CNTianjin Medical University · CNJackson Memorial Hospital · USUniversidade Federal de São Paulo · BR

Funding

National Natural Science Foundation of China 31871184National Natural Science Foundation of China 81830026Natural Science Foundation of Tianjin City 18ZXDBSY00030
6 · The paper itself

Abstract

backgroundProliferative diabetic retinopathy (PDR) is one of the most common cause of vision loss in diabetic patients, and the incidence age of PDR patients gradually gets younger. This study aims to compare the characteristics of PDR and outcomes following vitrectomy in young and senior patients.

methodsThis is a retrospective case series study. Data of 116 eyes of 92 patients who underwent vitrectomy for PDR from February 2012 to February 2017 were reviewed, which were divided into young and senior patient groups. All patients were followed up for 24 months at least.

resultsThere were 62.1% of eyes with tractional retinal detachment secondary to PDR in the young patient group, while only 12.1% of eyes in the senior patient group with this surgery indication. (P < 0.001) The best corrected visual acuity increased in 41 eyes (70.7%), stable in 9 eyes (15.5%), and decreased in 8 eyes (13.8%) in young patients at the final follow-up. And it increased in 47 eyes (81.0%), stable in 2 eyes (3.4%), and decreased in 9 eyes (15.5%) in senior patients.(P = 0.085) Postoperative complications mainly included recurrent vitreous hemorrhage (24.1%), retinal detachment (3.4%), neovascular glaucoma (NVG) (27.6%) and nuclear sclerosis (53.4%) in young patients, and it was 19.0, 0.0, 1.7 and 3.4% in senior patients respectively.

conclusionPDR of young patients is more severe than that of senior patients, and vitrectomy is an effective and safe method for PDR treatment. NVG is a main and severe complication besides nuclear sclerosis in young patients, and the incidence of NVG is higher compared to that in senior patients.

Indexed as

Diabetes MellitusDiabetic RetinopathyRetinal DetachmentHumansPostoperative ComplicationsRetrospective StudiesVisual AcuityVitrectomyNeovascular glaucomaProliferative diabetic retinopathyVitrectomyYoung patients

Identifiers

PMID33076873
PMCPMC7574415
OpenAlexW3092932130

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.