Evidence map›Paper›PMID 33076872›Full record

Observational studyBMC nephrology2020

Bioelectrical impedance analysis-derived phase angle as a determinant of protein-energy wasting and frailty in maintenance hemodialysis patients: retrospective cohort study.

Masakazu Saitoh, Masumi Ogawa, Hisae Kondo, Kiichi Suga, Tetsuya Takahashi, Haruki Itoh, Yoichiro Tabata

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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  20. Phase angle and cellular health: inflammation and oxidative damage.Reviews in endocrine & metabolic disorders · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Masakazu SaitohDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, 3-2-12, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. m.saito.tl@juntendo.ac.jp.ORCID 0000-0001-8666-6353
Masumi OgawaMeiseikai Toyo Clinic Yachimata, Chiba, Japan.
Hisae KondoMeiseikai Toyo Clinic Yachimata, Chiba, Japan.
Kiichi SugaMeiseikai Toyo Clinic Yachimata, Chiba, Japan.
Tetsuya TakahashiDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, 3-2-12, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Haruki ItohDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Yoichiro TabataMeiseikai Toyo Clinic Yachimata, Chiba, Japan.
Juntendo University · JPSakakibara Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhase angle (PA), measured by bioelectrical impedance analysis (BIA) has been studied as indicator of nutritional status or muscle function in hemodialysis (HD) patients. It remains unclear if the phase angle is associated protein-energy wasting (PEW) or frailty, which are common complication in hemodialysis patients. The aim of this study is to determine whether BIA-derived PA is a marker of PEW or frailty in HD patients.

methodsThis retrospective observational study included 116 adult HD patients (35% female, 64 ± 12 years of age) in a single dialysis center. Patients were classified according to the PA quartiles into four groups; 1) first quartile: PA < 3.7°, 2) second quartile: PA 3.7-4.1°, 3) third quartile: PA 4.2-4.9°and 4) forth quartile: PA ≥ 5.0°. International Society of Renal Nutrition and Metabolism (ISRNM) criteria and Japanese version of Cardiovascular Health Study (J-CHS) criteria were used to identify PEW and frailty.

resultsThe lower PA group was associated with a greater risk of PEW (35% vs. 24% vs. 21% vs. 3%; p = 0.032), frailty (59% vs. 40% vs. 21% vs. 3%; p < 0.001). In multivariate logistic regression analysis, the first quartile group was at a significantly greater risk of both PEW and frailty compared with the fourth quartile group after adjusting for other confounding factors.

conclusionsLower PA was associated with a greater risk of PEW and frailty in HD patients.

Indexed as

Electric ImpedanceAgedFemaleFrailtyHeart Disease Risk FactorsHumansKidney Failure, ChronicMaleMiddle AgedProtein-Energy MalnutritionRenal DialysisRetrospective StudiesWasting SyndromeBioimpedance electrical analysisFrailtyHemodialysisPhase angleProtein energy wasting

Identifiers

PMID33076872
PMCPMC7574227
OpenAlexW3093124332

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.