Evidence map›Paper›PMID 33076841›Full record

ArticleBMC geriatrics2020

Low calf circumference is associated with frailty in diabetic adults aged over 80 years.

Yun-Xia Zhu, Yue Zhang, Yan-Yan Wang, Chen-Xi Ren, Jun Xu, Xiao-Yan Zhang

Abstract read
In one paragraph

Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. IS CALF CIRCUMFERENCE ASSOCIATED WITH CLINICAL AND NUTRITIONAL OUTCOME IN OLDER PATIENTS?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yun-Xia ZhuDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Road Yi Shan 600, Shanghai, 200233, China.
Yue ZhangDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Road Yi Shan 600, Shanghai, 200233, China.
Yan-Yan WangDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Road Yi Shan 600, Shanghai, 200233, China.
Chen-Xi RenDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Road Yi Shan 600, Shanghai, 200233, China.
Jun XuDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Road Yi Shan 600, Shanghai, 200233, China.
Xiao-Yan ZhangDepartment of Geriatrics, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Road Yi Shan 600, Shanghai, 200233, China. zhangxy971088@hotmail.com.ORCID 0000-0002-1261-0960

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrailty is now seen as a significant factor in older people with diabetes, whose mortality and disability increased. This study aims to investigate the association between calf circumference (CC) with frailty in diabetic adults aged over 80 years.

methodsA cross-sectional analysis was performed on the data of 426 diabetic adults aged over 80 years. On admission, demographic data and laboratory parameters were recorded. CC was measured on the lower right leg at the point of the maximal circumference. All participants accepted frailty assessments. Frailty was mainly defined using the Fried frailty phenotype criteria.

resultsThe CC levels were significantly lower in the frail than the non-frail (26.7 ± 4.0 vs. 31.2 ± 4.0, P < 0.001). CC was negatively correlated with the Fried frailty phenotype index (P < 0.001). Logistic regression analysis of frailty revealed that age (Odds Ratio (OR), 1.368; 95% Confidential Interval (CI) 1.002-1.869; P = 0.049), CC (OR, 0.756; 95%CI 0.598-0.956; P = 0.019) were independent impact factors of frailty after adjusting all the potential confounders. Participants with low CC tertile had a significantly higher Fried frailty phenotype index than those with high CC tertiles. The best CC cut-off value for predicting frailty was 29.3 cm, its sensitivity was 75.0%, and the specificity was 78.6%, and areas under the curve (AUC) was 0.786 (P < 0.001).

conclusionsCC was strongly related to frailty in diabetic adults aged over 80 years, suggesting that CC may be helpful for monitoring physical frailty in older adults in clinical and research settings.

Indexed as

Diabetes MellitusFrailtyAgedAged, 80 and overCross-Sectional StudiesFrail ElderlyGeriatric AssessmentHumansLegAgingCalf circumferenceDiabetesFrailty

Identifiers

PMID33076841
PMCPMC7574465

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.