Evidence map›Paper›PMID 33076749›Full record

ArticleJournal of the American Heart Association2020

Risk Factors for Mortality and Circulatory Outcome Among Neonates Prenatally Diagnosed With Ebstein Anomaly or Tricuspid Valve Dysplasia: A Multicenter Study.

Lindsay R Freud, Doff B McElhinney, Brian T Kalish, Maria C Escobar-Diaz, Rukmini Komarlu, Michael D Puchalski, Edgar T Jaeggi, Anita L Szwast, Grace Freire, Stéphanie M Levasseur and 19 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 48 citations in OpenAlex.

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  11. Severe form of Ebstein's anomaly associated with ventricular septal defect.General thoracic and cardiovascular surgery cases · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 20 institutions in 3 countries.

Lindsay R FreudDivision of Cardiology Department of Pediatrics NewYork-Presbyterian Morgan Stanley Children's Hospital Columbia University Medical Center New York NY.
Doff B McElhinneyDivision of Cardiology Department of Pediatrics Lucile Packard Children's Hospital Stanford School of Medicine Palo Alto CA.
Brian T KalishDivision of Newborn Medicine Department of Pediatrics Boston Children's Hospital Harvard Medical School Boston MA.
Maria C Escobar-DiazDepartment of Pediatric Cardiology Hospital Sant Joan de Déu Universitat de Barcelona Spain.
Rukmini KomarluDivision of Pediatric Cardiology Department of Pediatrics Cleveland Clinic Children's Hospital Lerner College of Medicine at Case Western Reserve University Cleveland OH.
Michael D PuchalskiDivision of Cardiology Department of Pediatrics Primary Children's Hospital University of Utah School of Medicine Salt Lake City UT.
Edgar T JaeggiDivision of Cardiology Department of Paediatrics Hospital for Sick Children University of Toronto Toronto Ontario Canada.
Anita L SzwastDivision of Cardiology Department of Pediatrics Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Grace FreireDivision of Cardiology Department of Pediatrics Johns Hopkins All Children's Hospital St. Petersburg FL.
Stéphanie M LevasseurDivision of Cardiology Department of Pediatrics NewYork-Presbyterian Morgan Stanley Children's Hospital Columbia University Medical Center New York NY.
Ann Kavanaugh-McHughDivision of Cardiology Department of Pediatrics Monroe Carell Jr. Children's Hospital Vanderbilt University School of Medicine Nashville TN.
Erik C MichelfelderDivision of Cardiology Department of Pediatrics Children's Healthcare of Atlanta Sibley Heart Center Emory University School of Medicine Atlanta GA.
Anita J Moon-GradyDivision of Cardiology Department of Pediatrics UCSF Benioff Children's Hospital University of California-San Francisco School of Medicine San Francisco CA.
Mary T DonofrioDivision of Cardiology Department of Pediatrics Children's National Medical Center George Washington University School of Medicine and Health Sciences Washington DC.
Lisa W HowleyDivision of Cardiology Department of Pediatrics Children's Hospital Colorado University of Colorado School of Medicine Aurora CO.
Elif Seda Selamet TierneyDivision of Cardiology Department of Pediatrics Lucile Packard Children's Hospital Stanford School of Medicine Palo Alto CA.
Bettina F CuneoDivision of Cardiology Department of Pediatrics Children's Hospital Colorado University of Colorado School of Medicine Aurora CO.
Shaine A MorrisDivision of Cardiology Department of Pediatrics Texas Children's Hospital Baylor College of Medicine Houston TX.
Jay D PruetzDivision of Cardiology Department of Pediatrics Children's Hospital Los Angeles University of Southern California Keck School of Medicine Los Angeles CA.
Mary E van der VeldeDivision of Cardiology Department of Pediatrics University of Michigan Congenital Heart Center C.S. Mott Children's Hospital University of Michigan Medical School Ann Arbor MI.
John P KovalchinDivision of Cardiology Department of Pediatrics Nationwide Children's Hospital Ohio State University College of Medicine Columbus OH.
Catherine M IkembaDivision of Cardiology Department of Pediatrics Children's Medical Center University of Texas Southwestern Medical School Dallas TX.
Margaret M VernonDivision of Cardiology Department of Pediatrics Seattle Children's Hospital University of Washington School of Medicine Seattle WA.
Cyrus SamaiDivision of Cardiology Department of Pediatrics Children's Healthcare of Atlanta Emory University School of Medicine Atlanta GA.
Gary M SatouDivision of Cardiology Department of Pediatrics Mattel Children's Hospital University of California-Los Angeles David Geffen School of Medicine Los Angeles CA.
Nina L GotteinerDivision of Cardiology Department of Pediatrics Ann & Robert H. Lurie Children's Hospital of Chicago Northwestern University Feinberg School of Medicine Chicago IL.
Colin K PhoonDivision of Cardiology Department of Pediatrics Hassenfeld Children's Hospital at NYU Langone New York University School of Medicine New York NY.
Norman H SilvermanDivision of Cardiology Department of Pediatrics Lucile Packard Children's Hospital Stanford School of Medicine Palo Alto CA.
Wayne TworetzkyDepartment of Cardiology Boston Children's Hospital Harvard Medical School Boston MA.
Lucile Packard Children's Hospital · USBoston Children's Hospital · USChildren's Hospital Colorado · USEmory University · USMorgan Stanley Children's Hospital · USBaylor College of Medicine · USChildren's Hospital of Philadelphia · USChildren's Medical Center · USChildren's National · USCleveland Clinic Lerner College of Medicine · USHospital Sant Joan de Déu Barcelona · ESJohns Hopkins University · USMonroe Carell Jr. Children's Hospital · USNationwide Children's Hospital · USNew York University · USNorthwestern University · USPrimary Children's Hospital · USSeattle Children's Hospital · USUniversity of California, Los Angeles · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background In a recent multicenter study of perinatal outcome in fetuses with Ebstein anomaly or tricuspid valve dysplasia, we found that one third of live-born patients died before hospital discharge. We sought to further describe postnatal management strategies and to define risk factors for neonatal mortality and circulatory outcome at discharge. Methods and Results This 23-center, retrospective study from 2005 to 2011 included 243 fetuses with Ebstein anomaly or tricuspid valve dysplasia. Among live-born patients, clinical and echocardiographic factors were evaluated for association with neonatal mortality and palliated versus biventricular circulation at discharge. Of 176 live-born patients, 7 received comfort care, 11 died <24 hours after birth, and 4 had insufficient data. Among 154 remaining patients, 38 (25%) did not survive to discharge. Nearly half (46%) underwent intervention. Mortality differed by procedure; no deaths occurred in patients who underwent right ventricular exclusion. At discharge, 56% of the cohort had a biventricular circulation (13% following intervention) and 19% were palliated. Lower tricuspid regurgitation jet velocity (odds ratio [OR], 2.3 [1.1-5.0], 95% CI, per m/s;

Indexed as

Blood Flow VelocityEbstein AnomalyEchocardiographyFemaleHeart Valve DiseasesHospital MortalityHumansInfant, NewbornLogistic ModelsMalePerinatal MortalityPrenatal DiagnosisRetrospective StudiesRisk FactorsTricuspid Valvecongenital heart diseaseEbstein anomalymortalityneonateoutcomepalliationright ventricletricuspid regurgitation

Identifiers

PMID33076749
PMCPMC7763426
OpenAlexW3093459294

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.