Evidence map›Paper›PMID 33076505›Full record

ArticleCancers2020

Systematic Review and Meta-Analysis of Vesical Imaging-Reporting and Data System (VI-RADS) Inter-Observer Reliability: An Added Value for Muscle Invasive Bladder Cancer Detection.

Francesco Del Giudice, Martina Pecoraro, Hebert Alberto Vargas, Stefano Cipollari, Ettore De Berardinis, Marco Bicchetti, Benjamin I Chung, Carlo Catalano, Yoshifumi Narumi, James W F Catto and 1 more

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Current Status and Future Perspective for Bladder Cancer MR Imaging and the Vesical Imaging-Reporting and Data System (VI-RADS) in Japan: Challenges and Solutions.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Review
  7. Article
  8. Review
  9. 2025 Canadian Urological Association Expert Report: Muscle-invasive bladder cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  10. Review
  11. Gold nanorod-assisted theranostic solution for nonvisible residual disease in bladder cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco Del GiudiceDepartment of Maternal-Infant and Urological Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.ORCID 0000-0003-3865-5988
Martina PecoraroDepartment of Radiological Sciences, Oncology and Pathology, "Sapienza"/Policlinico Umberto I, 00161 Rome, Italy.
Hebert Alberto VargasDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Stefano CipollariDepartment of Radiological Sciences, Oncology and Pathology, "Sapienza"/Policlinico Umberto I, 00161 Rome, Italy.
Ettore De BerardinisDepartment of Maternal-Infant and Urological Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.
Marco BicchettiDepartment of Radiological Sciences, Oncology and Pathology, "Sapienza"/Policlinico Umberto I, 00161 Rome, Italy.
Benjamin I ChungDepartment of Urology, Stanford University, School of Medicine, Stanford, CA 94305, USA.
Carlo CatalanoDepartment of Radiological Sciences, Oncology and Pathology, "Sapienza"/Policlinico Umberto I, 00161 Rome, Italy.
Yoshifumi NarumiDepartments of Radiology and Health Science, Kyoto Tachibana University, Kyoto 607-8175, Japan.
James W F CattoAcademic Urology Unit, University of Sheffield, Sheffield S10 2TN, UK.
Valeria PanebiancoDepartment of Radiological Sciences, Oncology and Pathology, "Sapienza"/Policlinico Umberto I, 00161 Rome, Italy.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The Vesical Imaging-Reporting and Data System (VI-RADS) has been introduced to provide preoperative bladder cancer staging and has proved to be reliable in assessing the presence of muscle invasion in the pre-TURBT (trans-urethral resection of bladder tumor). We aimed to assess through a systematic review and meta-analysis the inter-reader variability of VI-RADS criteria for discriminating non-muscle vs. muscle invasive bladder cancer (NMIBC, MIBC). PubMed, Web of Science, Cochrane, and Embase were searched up until 30 July 2020. The Quality Appraisal of Diagnostic Reliability (QAREL) checklist was utilized to assess the quality of included studies and a pooled measure of inter-rater reliability (Cohen's Kappa [κ] and/or Intraclass correlation coefficients (ICCs)) was calculated. Further sensitivity analysis, subgroup analysis, and meta-regression were conducted to investigate the contribution of moderators to heterogeneity. In total, eight studies between 2018 and 2020, which evaluated a total of 1016 patients via 21 interpreting genitourinary (GU) radiologists, met inclusion criteria and were critically examined. No study was considered to be significantly flawed with publication bias. The pooled weighted mean κ estimate was 0.83 (95%CI: 0.78-0.88). Heterogeneity was present among the studies (Q = 185.92, d.f. = 7,

Indexed as

bladder cancerbladder cancer staginginter-reader agreementmultiparametric magnetic resonance imagingmuscle-invasive bladder cancerVI-RADS

Identifiers

PMID33076505
PMCPMC7602537

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.