Evidence map›Paper›PMID 33076496›Full record

ArticleBiomedicines2020

S-Methylcysteine (SMC) Ameliorates Intestinal, Hepatic, and Splenic Damage Induced by

Ehab Kotb Elmahallawy, Gehad E Elshopakey, Amira A Saleh, Ahmad Agil, Ahmed El-Morsey, Dina M M El-Shewehy, Ahmed S Sad, Tokuma Yanai, Walied Abdo

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  4. Evaluation of potential antiparasitic effect of ZnO nanoparticles on experimental cryptosporidiosis in immunosuppressed mice.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
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  8. Eugenol: effective complementary treatment for cryptosporidiosis in experimentally infected mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  9. Article
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  14. Article
  15. Article
  16. Acaricidal Properties of Four Neem Seed Extracts (Frontiers in veterinary science · 2022
    Article
  17. Article
  18. Article
  19. Hepatosplenic Protective Actions ofFrontiers in veterinary science · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 3 countries.

Ehab Kotb ElmahallawyDepartment of Zoonoses, Faculty of Veterinary Medicine, Sohag University, Sohag 82524, Egypt.ORCID 0000-0003-4484-3678
Gehad E ElshopakeyDepartment of Clinical Pathology, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.
Amira A SalehDepartment of Medical Parasitology, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.
Ahmad AgilDepartment of Pharmacology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.ORCID 0000-0003-0164-9648
Ahmed El-MorseyParasitology and Animal Diseases Department, Veterinary Research Division, National Research Centre, 33 El Buhouth St. (former El-Tahrir St.), Dokki, P.O., Giza 18010, Egypt.ORCID 0000-0001-5105-9465
Dina M M El-ShewehyZoology Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.ORCID 0000-0002-5915-777X
Ahmed S SadDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Port Said University, Port Fuad 42526, Egypt.
Tokuma YanaiLaboratory of Wildlife and Forensic Pathology, Biomedical Science Examination and Research Center, Department of Veterinary Medicine, Faculty of Veterinary Medicine, Okayama University of Science, Okayama 700-0005, Japan.
Walied AbdoDepartment of Pathology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr el-Sheikh 33516, Egypt.ORCID 0000-0003-4635-8342
Mansoura University · EGKafrelsheikh University · EGNational Research Centre · EGOkayama University of Science · JPPort Said University · EGUniversidad de Granada · ESUniversidad de León · ESZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptosporidiosis has been proposed to be one of the major causes of diarrhoeal disease in humans worldwide that possesses zoonotic concern. Thereby, this study investigated the potential effects of s-Methylcysteine (SMC) on the parasite in vivo followed by the measurement of cytokines, oxidative stress parameters, and an investigation of the major histopathological changes. Sixty male Swiss albino mice weighing 20-25 g were allocated equally into five groups and orally administered saline only (control), SMC only (SMC50) (50 mg/kg b.w.), and 10

Indexed as

Cryptosporidium parvumhepatic damageinflammatory biomarkersintestinal injurys-Methylcysteine

Identifiers

PMID33076496
PMCPMC7602666
OpenAlexW3093014188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.