Evidence map›Paper›PMID 33076422›Full record

ArticleJournal of clinical medicine2020

Diagnostic Power of Galectin-3 in Rheumatic Diseases.

Ewa Gruszewska, Bogdan Cylwik, Ewa Gińdzieńska-Sieśkiewicz, Otylia Kowal-Bielecka, Barbara Mroczko, Lech Chrostek

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ewa GruszewskaDepartment of Biochemical Diagnostics, Medical University of Bialystok, Waszyngtona St. 15A, 15-269 Bialystok, Poland.ORCID 0000-0002-7702-5148
Bogdan CylwikDepartment of Pediatric Laboratory Diagnostics, Medical University of Bialystok, Waszyngtona St. 17, 15-274 Bialystok, Poland.ORCID 0000-0002-9890-7334
Ewa Gińdzieńska-SieśkiewiczDepartment of Rheumatology and Internal Diseases, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Otylia Kowal-BieleckaDepartment of Rheumatology and Internal Diseases, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Barbara MroczkoDepartment of Biochemical Diagnostics, Medical University of Bialystok, Waszyngtona St. 15A, 15-269 Bialystok, Poland.ORCID 0000-0002-4075-8479
Lech ChrostekDepartment of Biochemical Diagnostics, Medical University of Bialystok, Waszyngtona St. 15A, 15-269 Bialystok, Poland.
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of our study was to assess the diagnostic power of galectin-3 and compare its between rheumatic diseases and with routinely used tests such as CRP and ESR.

methodsEighty-two patients with rheumatoid arthritis (RA), 49 patients with systemic sclerosis (SSc), and 18 patients with systemic lupus erythematosus (SLE) were enrolled in this study. The control group comprised 30 healthy controls. Serum galectin-3 concentration was measured using immunochemical method.

resultsThe galectin-3 concentration were significantly elevated in the RA, SSc, and SLE in comparison to the controls (

conclusionWe concluded that diagnostic power of serum galectin-3 is as great as CRP and ESR in rheumatic diseases and it can be a very good laboratory marker in RA and SSc patients and a useful tool in the diagnosis of SLE.

Indexed as

galectin-3rheumatoid arthritissystemic lupus erythematosussystemic sclerosis

Identifiers

PMID33076422
PMCPMC7602543
OpenAlexW3093011767

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.