Evidence map›Paper›PMID 33076318›Full record

ReviewMolecules (Basel, Switzerland)2020

Vibrational Spectroscopy for Identification of Metabolites in Biologic Samples.

Kevin V Hackshaw, Joseph S Miller, Didem P Aykas, Luis Rodriguez-Saona

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Review
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  8. Review
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  14. The Potential Use of Near- and Mid-Infrared Spectroscopy in Kidney Diseases.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Evaluation of the Cytotoxic Effect of PdInternational journal of molecular sciences · 2023
    Article
  19. Review
  20. Effects of NaturalMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Kevin V HackshawDepartment of Internal Medicine, Division of Rheumatology, Dell Medical School, The University of Texas, 1601 Trinity St, Austin, TX 78712, USA.
Joseph S MillerDepartment of Medicine, Ohio University Heritage College of Osteopathic Medicine, Dublin, OH 43016, USA.ORCID 0000-0001-6937-6880
Didem P AykasDepartment of Food Science and Technology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-5500-0441
Luis Rodriguez-SaonaDepartment of Food Science and Technology, Ohio State University, Columbus, OH 43210, USA.
The Ohio State University · USOhio University · USThe University of Texas at Austin · US

Funding

Objective tests utilizing Vibrational Spectroscopy for Diagnosis and Severity of Fibromyalgia and Related Pain SyndromesR61NS117211 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI HACKSHAW, KEVIN VICTOR, RODRIGUEZ-SAONA, LUIS E · 2020 to 2020
$1.5M
Columbus Medical Research Foundation 2019 - Kevin V. HackshawNINDS NIH HHS R61 NS117211
6 · The paper itself

Abstract

Vibrational spectroscopy (mid-infrared (IR) and Raman) and its fingerprinting capabilities offer rapid, high-throughput, and non-destructive analysis of a wide range of sample types producing a characteristic chemical "fingerprint" with a unique signature profile. Nuclear magnetic resonance (NMR) spectroscopy and an array of mass spectrometry (MS) techniques provide selectivity and specificity for screening metabolites, but demand costly instrumentation, complex sample pretreatment, are labor-intensive, require well-trained technicians to operate the instrumentation, and are less amenable for implementation in clinics. The potential for vibration spectroscopy techniques to be brought to the bedside gives hope for huge cost savings and potential revolutionary advances in diagnostics in the clinic. We discuss the utilization of current vibrational spectroscopy methodologies on biologic samples as an avenue towards rapid cost saving diagnostics.

Indexed as

MetabolomicsVibrationMagnetic Resonance SpectroscopyMetabolomeSpectrophotometry, InfraredSpectroscopy, Fourier Transform InfraredSpectrum Analysis, Ramanbiofluidbiomarkerdiagnosticsfingerprintinginfrared spectroscopymetabolitesRaman spectroscopyspectroscopyvibrational spectroscopy

Identifiers

PMID33076318
PMCPMC7587585
OpenAlexW3092733995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.