Evidence map›Paper›PMID 33076312›Full record

ArticleDiagnostics (Basel, Switzerland)2020

In Vivo Endoscopic Optical Coherence Tomography of the Healthy Human Oral Mucosa: Qualitative and Quantitative Image Analysis.

Marius Albrecht, Christian Schnabel, Juliane Mueller, Jonas Golde, Edmund Koch, Julia Walther

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
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  5. Article
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  7. Article
  8. Review
  9. Article
  10. A Quantitative Model for Optical Coherence Tomography.Sensors (Basel, Switzerland) · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marius AlbrechtTechnische Universitaet Dresden, Department of Medical Physics and Biomedical Engineering, Carl Gustav Carus Faculty of Medicine, Fetscherstraße 74, 01307 Dresden, Germany.
Christian SchnabelTechnische Universitaet Dresden, Department of Medical Physics and Biomedical Engineering, Carl Gustav Carus Faculty of Medicine, Fetscherstraße 74, 01307 Dresden, Germany.
Juliane MuellerTechnische Universität Dresden, Clinical Sensoring and Monitoring, Department of Anesthesiology and Intensive Care Medicine, Carl Gustav Carus Faculty of Medicine, Fetscherstraße 74, 01307 Dresden, Germany.
Jonas GoldeTechnische Universität Dresden, Clinical Sensoring and Monitoring, Department of Anesthesiology and Intensive Care Medicine, Carl Gustav Carus Faculty of Medicine, Fetscherstraße 74, 01307 Dresden, Germany.ORCID 0000-0002-8160-3000
Edmund KochTechnische Universität Dresden, Clinical Sensoring and Monitoring, Department of Anesthesiology and Intensive Care Medicine, Carl Gustav Carus Faculty of Medicine, Fetscherstraße 74, 01307 Dresden, Germany.
Julia WaltherTechnische Universitaet Dresden, Department of Medical Physics and Biomedical Engineering, Carl Gustav Carus Faculty of Medicine, Fetscherstraße 74, 01307 Dresden, Germany.
Technische Universität Dresden · DE

Funding

European Union/European Social424Fund (ESF) and the Free State of Saxony 10028430European Union/European Social Fund (ESF) and the Free State of Saxony 100270108Roland Ernst Foundation Dresden TOMScan
6 · The paper itself

Abstract

To date, there is still a lack of reliable imaging modalities to improve the quality of consultation, diagnostic and medical examinations of the oral mucosa in dentistry. Even though, optical technologies have become an important element for the detection and treatment of different diseases of soft tissue, for the case of oral screenings the evidence of the benefit in comparison to conventional histopathology is mostly still pending. One promising optical technology for oral diagnostics is optical coherence tomography (OCT). To prove the potential of OCT, even the amount of freely accessible OCT data is not sufficient to describe the variance of healthy human oral soft tissue in vivo. In order to remedy this deficiency, the present study provides in vivo OCT cross sections of the human oral mucosa of the anterior and posterior oral cavity as well as the oropharynx of 47 adult volunteers. A collection of representative OCT cross sections forms the basis for a randomized blinded image analysis by means of seven criteria to assess the main features of the superficial layers of the human oral mucosa and to determine its correlation to regional features known from hematoxylin and eosin (HE) stained histology.

Indexed as

adults, histologyendoscopyepithelial thicknesshealthy human oral mucosanoninvasiveoptical coherence tomography

Identifiers

PMID33076312
PMCPMC7602587
OpenAlexW3093235519

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.