Evidence map›Paper›PMID 33076282›Full record

ReviewNutrients2020

Understanding Development of Malnutrition in Hemodialysis Patients: A Narrative Review.

Sharmela Sahathevan, Ban-Hock Khor, Hi-Ming Ng, Abdul Halim Abdul Gafor, Zulfitri Azuan Mat Daud, Denise Mafra, Tilakavati Karupaiah

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 109 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 4 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04789031 nacompletednot on this map

Muscle Status to Oral Nutritional Supplementation in Hemodialysis Patients With Protein Energy Wasting

TypeinterventionalSponsorTaylor's UniversityRan2016 to 2019Enrolled54ConditionsMuscle Wasting, End Stage Renal Disease on DialysisArmsOral nutritional supplementation (ONS)
NCT06569732 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Efficacy, Feasibility, and Cost-effectiveness of Homemade Oral Nutrition Supplements on Patients on Hemodialysis With Protein-energy Wasting: a Parallel, Open-labeled, Randomized Controlled Trial

TypeinterventionalSponsorUniversiti Malaysia SabahRan2024 to 2025Enrolled40ConditionsProtein-Energy Wasting, Kidney Failure, HemodialysisArmsHomemade oral nutrition supplements, Commercial oral nutrition supplements
NCT07237997 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Re-examining Nutrition in Dialysis Patients: Nutritional Losses and the Role of Supplementation (Part 2).

TypeinterventionalSponsorUniversity of NottinghamRan2026 to 2029Enrolled114ConditionsDialysis Patients, Dialysis, Protein Energy Wasting, Protein IntakeArmsHigh Protein Diet/Modular protein supplements will be used
3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 4 syntheses or guidelines pooled it, 216 citations in OpenAlex.

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  4. Effects and safety ofFrontiers in pharmacology · 2024
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Sharmela SahathevanDietetics Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.
Ban-Hock KhorDepartment of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaakob Latif, Bandar Tun Razak, Cheras, 56000 Kuala Lumpur, Malaysia.
Hi-Ming NgSchool of Medicine, Faculty of Health & Medical Sciences, Taylor's University Lakeside Campus, No 1, Jalan Taylors, 47500 Subang Jaya, Malaysia.
Abdul Halim Abdul GaforDepartment of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaakob Latif, Bandar Tun Razak, Cheras, 56000 Kuala Lumpur, Malaysia.
Zulfitri Azuan Mat DaudDepartment of Dietetics, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Malaysia.
Denise MafraPost Graduation Program in Medical Sciences and Post-Graduation Program in Cardiovascular Sciences, (UFF), Federal Fluminense University Niterói-Rio de Janeiro (RJ), Niterói-RJ 24033-900, Brazil.
Tilakavati KarupaiahSchool of BioSciences, Faculty of Health & Medical Sciences, Taylor's University Lakeside Campus, No 1, Jalan Taylors, 47500 Subang Jaya, Malaysia.
National University of Malaysia · MYTaylor's University · MYUniversidade Federal Fluminense · BRUniversiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemodialysis (HD) majorly represents the global treatment option for patients with chronic kidney disease stage 5, and, despite advances in dialysis technology, these patients face a high risk of morbidity and mortality from malnutrition. We aimed to provide a novel view that malnutrition susceptibility in the global HD community is either or both of iatrogenic and of non-iatrogenic origins. This categorization of malnutrition origin clearly describes the role of each factor in contributing to malnutrition. Low dialysis adequacy resulting in uremia and metabolic acidosis and dialysis membranes and techniques, which incur greater amino-acid losses, are identified modifiable iatrogenic factors of malnutrition. Dietary inadequacy as per suboptimal energy and protein intakes due to poor appetite status, low diet quality, high diet monotony index, and/or psychosocial and financial barriers are modifiable non-iatrogenic factors implicated in malnutrition in these patients. These factors should be included in a comprehensive nutritional assessment for malnutrition risk. Leveraging the point of origin of malnutrition in dialysis patients is crucial for healthcare practitioners to enable personalized patient care, as well as determine country-specific malnutrition treatment strategies.

Indexed as

AcidosisDietary ProteinsEatingEnergy IntakeFemaleHumansMaleMalnutritionNutritional Physiological PhenomenaNutrition AssessmentRenal DialysisRenal Insufficiency, ChronicUremiaDietary Proteinshemodialysisiatrogenicmalnutritionnon-iatrogenic factors

Identifiers

PMID33076282
PMCPMC7602515
OpenAlexW3093411401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.