Evidence map›Paper›PMID 33075534›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Presenting Symptoms and Predictors of Poor Outcomes Among 2,184 Patients with COVID-19 in Lagos State, Nigeria.

Akin Abayomi, Oluwakemi Odukoya, Akin Osibogun, Ololade Wright, Bisola Adebayo, Mobolanle Balogun, Ismael Abdus-Salam, Abimbola Bowale, Bamidele Mutiu, Babatunde Saka and 14 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Akin AbayomiLagos State Ministry of Health.
Oluwakemi OdukoyaCollege of Medicine University of Lagos.
Akin OsibogunCollege of Medicine University of Lagos; Lagos State Primary Health Care Board; Lagos University Teaching Hospital. Electronic address: akinosibogun@yahoo.co.uk.
Ololade WrightLagos State University College of Medicine.
Bisola AdebayoLagos State University College of Medicine.
Mobolanle BalogunCollege of Medicine University of Lagos.
Ismael Abdus-SalamLagos State Ministry of Health.
Abimbola BowaleMainland Hospital, Yaba, Lagos, Nigeria.
Bamidele MutiuLagos State Biobank.
Babatunde SakaLagos State Biobank.
Moyosore AdejumoLagos State Ministry of Health.
Sam YenyiWorld Health Organization, Nigeria Office.
Rotimi AgbolagoriteLagos State Ministry of Health.
Oluwatosin OnasanyaLagos State Primary Health Care Board.
Eniola ErinoshoLagos State Primary Health Care Board.
Joshua ObasanyaNigeria Centre for Disease Control.
Olu AdejumoMainland Hospital, Yaba, Lagos, Nigeria.
Sunday AdesolaMainland Hospital, Yaba, Lagos, Nigeria.
Yewande OshodiCollege of Medicine University of Lagos; Lagos University Teaching Hospital.
Iorhen E AkaseLagos University Teaching Hospital.
Shina OgunbiyiMainland Hospital, Yaba, Lagos, Nigeria.
Dayo LajideLagos State Ministry of Health.
Femi ErinosoLagos State University Teaching Hospital.
Hussein Abdur-RazzaqLagos State Ministry of Health.

Funding

Promoting Physical Activity and Healthy Eating Among Adults in a Faith-Based Setting In Lagos, Nigeria.K43TW010704 · FIC · COLLEGE OF MEDICINE, UNIVERSITY OF LAGOS · PI ODUKOYA, OLUWAKEMI · 2017 to 2021
$501k
FIC NIH HHS K43 TW010704World Health Organization 001
6 · The paper itself

Abstract

introductionLagos state remains the epicentre of COVID-19 in Nigeria. We describe the symptoms and signs of the first 2,184 PCR-confirmed COVID-19 patients admitted at COVID-19 treatment centers in Lagos State. We also assessed the relationship between patients' presenting symptoms, sociodemographic and clinical characteristics and COVID-19 deaths..

methodsMedical records of PCR-confirmed COVID-19 patients were extracted and analyzed for their symptoms, symptom severity, presence of comorbidities and outcome.

resultsThe ages of the patients ranged from 4 days to 98 years with a mean of 43.0(16.0) years. Of the patients who presented with symptoms, cough (19.3%) was the most common presenting symptom. This was followed by fever (13.7%) and difficulty in breathing, (10.9%). The most significant clinical predictor of death was the severity of symptoms and signs at presentation. Difficulty in breathing was the most significant symptom predictor of COVID-19 death (OR:19.26 95% CI 10.95-33.88). The case fatality rate was 4.3%.

conclusionPrimary care physicians and COVID-19 frontline workers should maintain a high index of suspicion and prioritize the care of patients presenting with these symptoms. Community members should be educated on such predictors and ensure that patients with these symptoms seek care early to reduce the risk of deaths associated with COVID-19.

Indexed as

SARS-CoV-2AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCOVID-19FemaleHumansInfantInfant, NewbornMaleMiddle AgedNigeriaYoung AdultCOVID-19DeathNigeriaSymptoms

Identifiers

PMID33075534
PMCPMC7566672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.