Evidence map›Paper›PMID 33075381›Full record

ArticleUrology2021

Promotional Payments Made to Urologists by the Pharmaceutical Industry and Prescribing Patterns for Targeted Therapies.

Brent K Hollenbeck, Mary Oerline, Samuel R Kaufman, Megan E V Caram, Stacie B Dusetzina, Andy M Ryan, Vahakn B Shahinian

Abstract read
In one paragraph

Article in Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Brent K HollenbeckDepartments of Urology, University of Michigan, Ann Arbor, MI. Electronic address: bhollen@med.umich.edu.
Mary OerlineDepartments of Urology, University of Michigan, Ann Arbor, MI.
Samuel R KaufmanDepartments of Urology, University of Michigan, Ann Arbor, MI.
Megan E V CaramMedicine, University of Michigan, Ann Arbor, MI.
Stacie B DusetzinaDepartment of Health Policy, Vanderbilt University School of Medicine, Nashville, TN.
Andy M RyanHealth Management and Policy, University of Michigan, Ann Arbor, MI.
Vahakn B ShahinianDepartments of Urology, University of Michigan, Ann Arbor, MI; Medicine, University of Michigan, Ann Arbor, MI.

Funding

Impact of urologist practice organization and health policy on prostate cancer treatment, overtreatment and spendingR01HS025707 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOLLENBECK, BRENT K., SHAHINIAN, VAHAKN B · 2017 to 2021
$1.7M
AHRQ HHS R01 HS025707
6 · The paper itself

Abstract

objectiveTo measure the association between market-level promotional payments to urologists by the manufacturers of abiraterone and enzalutamide and national prescribing patterns.

methodsA 20% national sample of the 2015 Part D event file was used to identify patients filling their first prescription for abiraterone and enzalutamide and their prescribing physicians. The 2015 Open Payments data were used to characterize promotional payments made to physicians at the market level. Generalized linear models were then used to measure the relationship between market-level payments to urologists and the physician specialty prescribing abiraterone or enzalutamide for the first time

resultsIn 2015, 2318 men filled a prescription for abiraterone or enzalutamide by a urologist or medical oncologist. Increasing market-level promotional payments to urologists for abiraterone or enzalutamide was strongly associated with a urologist prescribing either drug-24.3% versus 5.8% of those residing in the markets with highest and lowest level of promotional payments to urologists, respectively (P <.01). Neither the number of urologists residing in a market nor other promotional payment measures (ie, to medical oncologists for these drugs, or to all physicians for all other drugs) were associated with a urologist prescribing either drug.

conclusionPromotional payments to urologists at the market level are strongly associated with the specialty of the physician prescribing abiraterone or enzalutamide for the first time. Future work should elucidate the effects of the shift in prescribing patterns on quality of care and financial hardship for men with advanced prostate cancer.

Indexed as

AgedAndrostenesBenzamidesDrug IndustryDrug PrescriptionsHumansMaleMedicare Part DNitrilesPhenylthiohydantoinPractice Patterns, Physicians'United StatesUrologistsabirateroneAndrostenesBenzamidesenzalutamideNitrilesPhenylthiohydantoin

Identifiers

PMID33075381
PMCPMC7870542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.