Evidence map›Paper›PMID 33075113›Full record

ArticlePloS one2020

Evaluation of viral co-infections among patients with community-associated Clostridioides difficile infection.

Lauren Korhonen, Jessica Cohen, Nicole Gregoricus, Monica M Farley, Rebecca Perlmutter, Stacy M Holzbauer, Ghinwa Dumyati, Zintars Beldavs, Ashley Paulick, Jan Vinjé and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Clinical Characteristics and Risk Factors ofJournal of clinical medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Lauren KorhonenDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Jessica CohenDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Nicole GregoricusDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Monica M FarleyEmory University School of Medicine, Atlanta, Georgia, United States of America.
Rebecca PerlmutterMaryland Department of Health, Baltimore, Maryland, United States of America.
Stacy M HolzbauerMinnesota Department of Health, St Paul, Minnesota, United States of America.
Ghinwa DumyatiNew York Emerging Infections Program and University of Rochester Medical Center, Rochester, New York, United States of America.
Zintars BeldavsOregon Health Authority, Portland, Oregon, United States of America.
Ashley PaulickDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Jan VinjéDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Brandi M LimbagoDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Fernanda C LessaDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Alice Y GuhDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.ORCID 0000-0002-3141-2089
Centers for Disease Control and Prevention · USEmory University · USMaryland Department of Health · USOregon Health Authority · USUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed viral co-infections in 155 patients with community-associated Clostridioides difficile infection in five U.S. sites during December 2012-February 2013. Eighteen patients (12%) tested positive for norovirus (n = 10), adenovirus (n = 4), rotavirus (n = 3), or sapovirus (n = 1). Co-infected patients were more likely than non-co-infected patients to have nausea or vomiting (56% vs 31%; p = 0.04), suggesting that viral co-pathogens contributed to symptoms in some patients. There were no significant differences in prior healthcare or medication exposures or in CDI complications.

Indexed as

CoinfectionVirus DiseasesAdenoviridaeAdolescentAdultAgedChildChild, PreschoolClostridioides difficileClostridium InfectionsCommunity-Acquired InfectionsFecesFemaleHumansMaleMiddle Aged

Identifiers

PMID33075113
PMCPMC7571680
OpenAlexW3092941274

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.