ArticleEnvironmental health perspectives2020
Association between Kawasaki Disease and Prenatal Exposure to Ambient and Industrial Air Pollution: A Population-Based Cohort Study.
Article in Environmental health perspectives, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early life exposure to ambient particulate matter and Kawasaki disease: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Spatiotemporal analysis of the association between Kawasaki disease incidence and PMBMJ paediatrics open · 2024Article
- Environmental Exposures and Pediatric Cardiology: A Scientific Statement From the American Heart Association.Circulation · 2024Review
- Prenatal and early life exposure to air pollution and the incidence of Kawasaki disease.Scientific reports · 2022Article
- Tooth biomarkers to characterize the temporal dynamics of the fetal and early-life exposome.Environment international · 2021Article
- Socioeconomic and Racial and/or Ethnic Disparities in Multisystem Inflammatory Syndrome.Pediatrics · 2021Article
- Impact of climate change on rheumatic diseases: A scoping review.The journal of climate change and healthReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnvironmental factors may contribute to the development of Kawasaki disease in children, but prenatal environmental exposures are understudied.
objectiveWe used a population-based cohort to investigate whether prenatal exposure to outdoor air pollution is associated with the incidence of Kawasaki disease in childhood.
methodsWe performed a longitudinal cohort study of all children born in Quebec, Canada, between 2006 and 2012. Children were followed for Kawasaki disease from birth until 31 March 2018. We assigned prenatal air pollutant exposure according to the residential postal code at birth. The main exposure was annual average concentration of ambient fine particulate matter [PM
resultsThe cohort comprised 505,336 children, including 539 with Kawasaki disease. HRs for each interquartile range increase in ambient air pollution were 1.16 (95% CI: 0.96, 1.39) for DISCUSSION: In this population-based cohort study, both prenatal exposure to ambient and industrial air pollution were associated with the incidence of Kawasaki disease in childhood. Further studies are needed to consolidate the observed associations. https://doi.org/10.1289/EHP6920.
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