Evidence map›Paper›PMID 33074543›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Gene Editing in the Ascidian Phallusia mammillata and Tail Nerve Cord Formation.

Alex McDougall, Celine Hebras, Isa Gomes, Remi Dumollard

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 28 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alex McDougallLaboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Sorbonne Université/CNRS, Villefranche-sur-Mer, France. dougall@obs-vlfr.fr.
Celine HebrasLaboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Sorbonne Université/CNRS, Villefranche-sur-Mer, France.
Isa GomesLaboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Sorbonne Université/CNRS, Villefranche-sur-Mer, France.
Remi DumollardLaboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Sorbonne Université/CNRS, Villefranche-sur-Mer, France.
Centre National de la Recherche Scientifique · FRLaboratoire de Biologie du Développement de Villefranche-sur-Mer · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional approaches for studying embryonic development have greatly advanced thanks to the CRISPR-Cas9 gene editing technique. Previously practiced in just a few organisms, these knockout techniques are now widely applied. Here we describe simple techniques for applying the CRISPR-Cas9 system to study the development of the nerve cord in the ascidian Phallusia mammillata.

Indexed as

CRISPR-Cas SystemsAnimalsGene EditingMicroinjectionsUrochordataAscidianCRISPR-Cas9Gene editingMicroinjectionNerve cordPhallusia mammillata

Identifiers

PMID33074543
OpenAlexW3092810599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.