ArticleeLife2020
NAIP-NLRC4-deficient mice are susceptible to shigellosis.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed, 99 citations in OpenAlex.
- Article
- Host response to bacteria induces a shift towards the enteroendocrine cell lineage in the murine enteroid model.PLoS pathogens · 2026Article
- Gasdermins against intracellular bacterial pathogens.Nature microbiology · 2026Review
- Article
- Dual NLRC4 and non-canonical inflammasome signaling drives human GSDMD-mediated killing ofbioRxiv : the preprint server for biology · 2026Article
- Dysregulation of innate immune sensors and autoinflammation: insights from an NLRC4 mouse AIFEC model.Cellular & molecular immunology · 2026Article
- Shigella type-III secretion system effectors counteract the induction of host inflammation and cell death.The EMBO journal · 2025Article
- Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei.Nature communications · 2025Article
- Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ.Cell host & microbe · 2025Article
- Article
- Determinants of divergentmBio · 2025Article
- Organoid models advance dysentery control.Nature genetics · 2025Article
- The IL-18 receptor is expressed on murine small-intestinal enterochromaffin cells and executes a recovery program upon injury.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella.The Journal of experimental medicine · 2025Article
- Gasdermin-D pores induce an inactivating caspase-4 cleavage that limits IL-18 production in the intestinal epithelium.Communications biology · 2025Article
- Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions.Nature reviews. Microbiology · 2025Review
- A newly developed oral infection mouse model of shigellosis for immunogenicity and protective efficacy studies of a candidate vaccine.Infection and immunity · 2025Article
- Whole genome analysis ofFrontiers in veterinary science · 2025Article
- Spatial visualization provides insight into immune modulation by an L-DBF vaccine formulation againstFrontiers in immunology · 2025Article
- Inflammasome-mediated pyroptosis in defense against pathogenic bacteria.Immunological reviews · 2025Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Patrick S Mitchell *Division of Immunology & Pathogenesis, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, United States.
Justin L Roncaioli *Division of Immunology & Pathogenesis, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, United States.
Elizabeth A TurcotteDivision of Immunology & Pathogenesis, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, United States.
Lisa GoersDepartment of Microbiology, Harvard Medical School, Boston, United States.
Roberto A ChavezDivision of Immunology & Pathogenesis, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, United States.
Angus Y LeeCancer Research Laboratory, University of California, Berkeley, Berkeley, United States.
Cammie F LesserDepartment of Microbiology, Harvard Medical School, Boston, United States.
Isabella RauchDepartment of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, United States.
Russell E VanceDivision of Immunology & Pathogenesis, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-6686-3912
University of California, Berkeley · USBroad Institute · USHoward Hughes Medical Institute · USOregon Health & Science University · US
Funding
The role of Listeria cyclic-di-AMP during infection and immunityP01AI063302 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI PORTNOY, DANIEL A · 2004 to 2025
$45.5MTHE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4MModeling mechanisms of Shigella pathogenesis in yeastR01AI064285 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LESSER, CAMMIE · 2006 to 2017
$4.0MFunctional and Structural Dissection of Inflammasome ActivationR37AI075039 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI RUSSELL E VANCE · 2018 to 2026
$3.8MSpecificity and in vivo function of the Naip/Nlrc4 inflammasomesR01AI075039 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI VANCE, RUSSELL E · 2008 to 2017
$3.6MDissection of Shigella pathogenesis in vivo using a new oral infection mouse modelR01AI155634 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI VANCE, RUSSELL E · 2020 to 2024
$2.2MShigella suppression of epithelial cell deathR56AI064285 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LESSER, CAMMIE · 2012 to 2022
$948kShigella and macrophage cell deathR21AI128743 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LESSER, CAMMIE · 2017 to 2018
$470kHoward Hughes Medical InstituteMedical Research Foundation MRF2012NIAID NIH HHS P01 AI063302NIAID NIH HHS R01 AI064285NIAID NIH HHS R01 AI075039NIAID NIH HHS R01 AI155634NIAID NIH HHS R21 AI128743NIAID NIH HHS R37 AI075039NIAID NIH HHS R56 AI064285NIGMS NIH HHS T32 GM007232
Abstract
Bacteria of the genus
Indexed as
AnimalsApoptosis Regulatory ProteinsCalcium-Binding ProteinsDisease SusceptibilityDysentery, BacillaryHumansInflammasomesMiceMice, Inbred C57BLMice, KnockoutNeuronal Apoptosis-Inhibitory ProteinShigellaApoptosis Regulatory ProteinsCalcium-Binding ProteinsInflammasomesIpaf protein, mouseNaip1 protein, mouseNeuronal Apoptosis-Inhibitory Proteinimmunologyinfectious diseaseinflammasomeinflammationmicrobiologymouseShigellashigellosis
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.