Evidence map›Paper›PMID 33073420›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021

Enantioselective Aromatic Amination?

Vinzenz Thönnißen, Frederic W Patureau

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Cross-dehydrogenative N-N couplings.Chemical science · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vinzenz ThönnißenInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
Frederic W PatureauInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.ORCID http://orcid.org/0000-0002-4693-7240

Funding

European Research Council ERC project 716136: 2O2ACTIVATION
6 · The paper itself

Abstract

The atroposelective formation of C-N bonds has recently emerged within the field of amination reactions. On first sight, it may seem quite surprising that such an ancient class of organic coupling reactions (Gabriel, Ullmann, Goldberg, Buchwald, Hartwig and many others) has so few enantioselective solutions, and this in spite of asymmetric synthesis being now a mature concept and field. Why should enantioselective C-N bond formation be so difficult? This question and some of the first examples that promise an imminent change of paradigm are herein discussed.

Indexed as

atroposelective aminationBuchwald-HartwigChan-Lamenantioselective aminationUllmann-Goldberg

Identifiers

PMID33073420
PMCPMC8252738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.