Evidence map›Paper›PMID 33073315›Full record

ArticleWorld journal of surgery2021

Splenic Artery Angioembolization is Associated with Increased Venous Thromboembolism.

M Lewis, A Piccinini, E Benjamin, D Demetriades

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Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Surgical management of injuries to the abdomen in patients with multiple and/or severe trauma- a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
  2. Surgical management of injuries to the abdomen in patients with multiple and/or severe trauma- a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M LewisDivision of Acute Care Surgery, Department of Surgery , University of Southern California Medical Center, Inpatient Tower, 2051 Marengo Street, Room C5L100, Los Angeles, CA, 90033, USA. Meghan.lewis@med.usc.edu.ORCID http://orcid.org/0000-0002-3200-7771
A PiccininiDivision of Acute Care Surgery, Department of Surgery , University of Southern California Medical Center, Inpatient Tower, 2051 Marengo Street, Room C5L100, Los Angeles, CA, 90033, USA.
E BenjaminDivision of Acute Care Surgery, Department of Surgery , University of Southern California Medical Center, Inpatient Tower, 2051 Marengo Street, Room C5L100, Los Angeles, CA, 90033, USA.
D DemetriadesDivision of Acute Care Surgery, Department of Surgery , University of Southern California Medical Center, Inpatient Tower, 2051 Marengo Street, Room C5L100, Los Angeles, CA, 90033, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAngioembolization has become an increasingly utilized adjunct for splenic preservation after trauma. Embolization of the splenic artery may produce a transient systemic hypercoagulable state. This study was designed to determine the risk of venous thromboembolism (VTE) in blunt trauma patients managed nonoperatively with splenic angioembolization, relative to those managed without.

methodRetrospective review of the American College of Surgeons Trauma Quality Improvement Performance (TQIP) Database from 2013 to 2016. Adult (>16 years) patients with isolated, severe (Grades III-V) blunt splenic injuries managed nonoperatively who received pharmacological VTE prophylaxis formed the study population. Outcomes included deep venous thrombosis (DVT), pulmonary embolism (PE), or any VTE.

resultsA total of 2643 patients met inclusion criteria (69.1% Grade III, 26.5% Grade IV, 4.5% Grade V). The incidence of DVT was 4.5% in patients who underwent angioembolization, compared to 1.4% in patients who did not (p<0.001). Multivariable analysis showed that angioembolization was an independent risk factor for both DVT (OR 2.65, p = 0.006) and any VTE (OR 2.04, p = 0.01). Analysis according to splenic injury Grades showed that angioembolization remained an independent risk factor for DVT (p = 0.004) in the Grade IV-V injury group, and for VTE (p<0.01) in the Grade III injury group. Initiation of pharmacological VTE prophylaxis 48 h after admission was associated with increased VTE rates in comparison to early initiation (OR 1.75, p = 0.02)

conclusionsSplenic artery angioembolization may be an independent risk factor for VTE events in isolated, severe blunt splenic trauma managed nonoperatively. Early prophylaxis with LMWH after intervention should be strongly considered.

Indexed as

Pulmonary EmbolismSpleenSplenic ArteryVenous ThrombosisAbdominal InjuriesAdultAnticoagulantsDatabases, FactualEmbolization, TherapeuticFemaleHeparin, Low-Molecular-WeightHumansMaleMiddle AgedRetrospective StudiesVenous ThromboembolismAnticoagulantsHeparin, Low-Molecular-Weight

Identifiers

PMID33073315

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.