Evidence map›Paper›PMID 33073313›Full record

ArticleMikrochimica acta2020

Fluorescent turn-on assay of C-type natriuretic peptide using a molecularly imprinted ratiometric fluorescent probe with high selectivity and sensitivity.

Hongliang He, Min Cao, Jingwan Hu, Ling Zhu, Chang Su, Shuhu Du, Jian Yang, Yulin Tang, Lina Chen

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In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hongliang HeDepartment of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Min CaoCenter of Pathology and Clinical Laboratory, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211100, Jiangsu, China.
Jingwan HuDepartment of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Ling ZhuDepartment of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Chang SuDepartment of Pharmacy, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211100, Jiangsu, China.
Shuhu DuSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Jian YangDepartment of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, China. jianyang@njmu.edu.cn.
Yulin TangDepartment of Pharmacy, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211100, Jiangsu, China. ylt1964@sina.com.
Lina ChenSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China. chenlina@njmu.edu.cn.
Nanjing Medical University · CN

Funding

Jiangsu Salt Industry Group Co., Ltd NMU-SY201805Nanjing Health Science and Technology Development Special Fund YKK19173Natural Science Foundation of Jiangsu Province BK20191352
6 · The paper itself

Abstract

A novel molecularly imprinted ratiometric fluorescent probe was fabricated by simple sol-gel polymerization for selective and sensitive assay of C-type natriuretic peptide (CNP) in biosamples. Both the nitrobenzoxadiazole (NBD) and carbon dots (CDs) were located on the surface of silica, used as the detection signal and reference signal, respectively. For the turn-on-based probe, the fluorescence intensity of NBD could be quantitatively enhanced by CNP based on the strategy of photo-induced electron transfer (PET), while the fluorescence of CDs remained unchanged. The obtained probe exhibited excellent recognition selectivity and fast kinetics to CNP templates, and also showed good stability. The linear range of CNP determination was 5-80 pg mL

Indexed as

Electron TransportFluorescenceFluorescent DyesHumansMolecular ImprintingMolecular ProbesNatriuretic Peptide, C-TypeOxadiazolesQuantum DotsSensitivity and SpecificitySerumSilicon DioxideSpectrometry, FluorescenceFluorescent DyesMolecular ProbesNatriuretic Peptide, C-TypeOxadiazolesSilicon DioxideC-type natriuretic peptideMolecularly imprinted polymerRatiometric fluorescenceSerum samples

Identifiers

PMID33073313
OpenAlexW3093209339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.