Evidence map›Paper›PMID 33073255›Full record

ArticlePatterns (New York, N.Y.)2020

Detecting Asymmetric Patterns and Localizing Cancers on Mammograms.

Yuanfang Guan, Xueqing Wang, Hongyang Li, Zhenning Zhang, Xianghao Chen, Omer Siddiqui, Sara Nehring, Xiuzhen Huang

Abstract read
In one paragraph

Article in Patterns (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Multilevel Modeling of Joint Damage in Rheumatoid Arthritis.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuanfang GuanDepartment of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Xueqing WangDepartment of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Hongyang LiDepartment of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Zhenning ZhangDepartment of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Xianghao ChenDepartment of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Omer SiddiquiDepartment of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Sara NehringTranslational Research Lab of Arkansas State University and St. Bernard's Medical Center, Jonesboro, AR 72467, USA.
Xiuzhen HuangTranslational Research Lab of Arkansas State University and St. Bernard's Medical Center, Jonesboro, AR 72467, USA.

Funding

Machine Learning for Drug Response PredictionR35GM133346 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Yuanfang Guan · 2019 to 2026
$3.2M
NIGMS NIH HHS R35 GM133346
6 · The paper itself

Abstract

One in eight women develops invasive breast cancer in her lifetime. The frontline protection against this disease is mammography. While computer-assisted diagnosis algorithms have made great progress in generating reliable global predictions, few focus on simultaneously producing regions of interest (ROIs) for biopsy. Can we combine ROI-oriented algorithms with global classification of cancer status, which simultaneously highlight suspicious regions and optimize classification performance? Can the asymmetry of breasts be adopted in deep learning for finding lesions and classifying cancers? We answer the above questions by building deep-learning networks that identify masses and microcalcifications in paired mammograms, exclude false positives, and stepwisely improve performance of the model with asymmetric information regarding the breasts. This method achieved a co-leading place in the Digital Mammography DREAM Challenge for predicting breast cancer. We highlight here the importance of this dual-purpose process that simultaneously provides the locations of potential lesions in mammograms.

Identifiers

PMID33073255
PMCPMC7566852

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.