Evidence map›Paper›PMID 33073099›Full record

ArticleACS omega2020

Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions.

Tomás Sou, Fadi Soukarieh, Paul Williams, Michael J Stocks, Miguel Cámara, Christel A S Bergström

Abstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Design, Synthesis, and Evaluation of New 1Journal of medicinal chemistry · 2024
    Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tomás SouMolecular Pharmaceutics, Department of Pharmacy, Uppsala University, SE-751 23 Uppsala, Sweden.
Fadi SoukariehNottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Paul WilliamsNottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Michael J StocksNottingham University Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Miguel CámaraNottingham University Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Christel A S BergströmDrug Delivery, Department of Pharmacy, Uppsala University, SE-751 23 Uppsala, Sweden.

Funding

Medical Research Council MR/N501852/1
6 · The paper itself

Abstract

For respiratory conditions, targeted drug delivery to the lungs could produce higher local concentrations with reduced risk of adverse events compared to systemic administration. Despite the increasing interest in pulmonary delivery, the pharmacokinetics (PK) of drugs following pulmonary administration remains to be elucidated. In this context, the application of modeling and simulation methodologies to characterize PK properties of compounds following pulmonary administration remains a scarcity.

Identifiers

PMID33073099
PMCPMC7557213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.