Evidence map›Paper›PMID 33073029›Full record

ArticleInternational journal of neonatal screening2020

Newborn Screening for Cystic Fibrosis in Russia: A Catalyst for Improved Care.

Victoria Sherman, Elena Kondratyeva, Nataliya Kashirskaya, Anna Voronkova, Victoria Nikonova, Elena Zhekaite, Sergey Kutsev

Abstract read
In one paragraph

Article in International journal of neonatal screening, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Victoria ShermanResearch Centre for Medical Genetics, 115522 Moscow, Russia; elenafpk@mail.ru (E.K.); kashirskayanj@mail.ru (N.K.); voronkova111@yandex.ru (A.V.); nikonovavs@mail.ru (V.N.); elena_zhekayte@mail.ru (E.Z.); kutsev@mail.ru (S.K.).ORCID https://orcid.org/0000-0003-2206-1528
Elena KondratyevaResearch Centre for Medical Genetics, 115522 Moscow, Russia; elenafpk@mail.ru (E.K.); kashirskayanj@mail.ru (N.K.); voronkova111@yandex.ru (A.V.); nikonovavs@mail.ru (V.N.); elena_zhekayte@mail.ru (E.Z.); kutsev@mail.ru (S.K.).ORCID https://orcid.org/0000-0001-6395-0407
Nataliya KashirskayaResearch Centre for Medical Genetics, 115522 Moscow, Russia; elenafpk@mail.ru (E.K.); kashirskayanj@mail.ru (N.K.); voronkova111@yandex.ru (A.V.); nikonovavs@mail.ru (V.N.); elena_zhekayte@mail.ru (E.Z.); kutsev@mail.ru (S.K.).ORCID https://orcid.org/0000-0003-0503-6371
Anna VoronkovaResearch Centre for Medical Genetics, 115522 Moscow, Russia; elenafpk@mail.ru (E.K.); kashirskayanj@mail.ru (N.K.); voronkova111@yandex.ru (A.V.); nikonovavs@mail.ru (V.N.); elena_zhekayte@mail.ru (E.Z.); kutsev@mail.ru (S.K.).
Victoria NikonovaResearch Centre for Medical Genetics, 115522 Moscow, Russia; elenafpk@mail.ru (E.K.); kashirskayanj@mail.ru (N.K.); voronkova111@yandex.ru (A.V.); nikonovavs@mail.ru (V.N.); elena_zhekayte@mail.ru (E.Z.); kutsev@mail.ru (S.K.).
Elena ZhekaiteResearch Centre for Medical Genetics, 115522 Moscow, Russia; elenafpk@mail.ru (E.K.); kashirskayanj@mail.ru (N.K.); voronkova111@yandex.ru (A.V.); nikonovavs@mail.ru (V.N.); elena_zhekayte@mail.ru (E.Z.); kutsev@mail.ru (S.K.).
Sergey KutsevResearch Centre for Medical Genetics, 115522 Moscow, Russia; elenafpk@mail.ru (E.K.); kashirskayanj@mail.ru (N.K.); voronkova111@yandex.ru (A.V.); nikonovavs@mail.ru (V.N.); elena_zhekayte@mail.ru (E.Z.); kutsev@mail.ru (S.K.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to assess the effectiveness of the detection of cystic fibrosis (CF) patients by screening compared with diagnoses based on clinical manifestations, the data of the National CF Patient Registry (NCFPR) from the year 2012 (group I: children aged 6-9 years, diagnosed prior to the start of screening) were compared with the data in the NCFPR from the year 2015 (group II: children 6-9 years after the start of screening) for CF patients from the Moscow region. Homozygotes for c.1521_1523delCTT (F508del) were separately compared in both groups. The average diagnosis age, genotype, body mass index, spirometry data, pulmonary infection, medications, and presence of complications were analyzed. This study demonstrated that in the c.1521_1523delCTT (F508del) homozygote group, the patients diagnosed by screening had significant advantages over the patients born before the start of newborn screening in the diagnosis age, the number of patients with chronic

Indexed as

cystic fibrosisIRTnewborn screeningsweat test

Identifiers

PMID33073029
PMCPMC7423000

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.