Evidence map›Paper›PMID 33072887›Full record

ArticleJournal of psychiatry and brain science2020

Disrupted Eye Gaze Perception as a Biobehavioral Marker of Social Dysfunction: An RDoC Investigation.

Ivy F Tso, Carly A Lasagna, Kate D Fitzgerald, Costanza Colombi, Chandra Sripada, Scott J Peltier, Timothy D Johnson, Katharine N Thakkar

Open access · diamondAbstract read
In one paragraph

Article in Journal of psychiatry and brain science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ivy F TsoDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, MI 48109, USA.
Carly A LasagnaDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, MI 48109, USA.
Kate D FitzgeraldDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, MI 48109, USA.
Costanza ColombiDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, MI 48109, USA.
Chandra SripadaDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, MI 48109, USA.
Scott J PeltierFunctional MRI Laboratory, University of Michigan, Ann Arbor, Michigan, MI 48109, USA.
Timothy D JohnsonDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, MI 48109, USA.
Katharine N ThakkarDepartment of Psychology, Michigan State University, East Lansing, Michigan, MI 48824, USA.
University of Michigan–Ann Arbor · US

Funding

Disrupted eye gaze perception as a biobehavioral marker of social dysfunction: An RDoC investigationR01MH122491 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TSO, IVY FEI · 2020 to 2024
$2.9M
Neural mechanisms of eye gaze perception in schizophreniaK23MH108823 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TSO, IVY FEI · 2016 to 2020
$894k
NIMH NIH HHS K23 MH108823NIMH NIH HHS R01 MH122491
6 · The paper itself

Abstract

Social dysfunction is an intractable problem in a wide spectrum of psychiatric illnesses, undermining patients' capacities for employment, independent living, and maintaining meaningful relationships. Identifying common markers of social impairment across disorders and understanding their mechanisms are prerequisites to developing targeted neurobiological treatments that can be applied productively across diagnoses and illness stages to improve functional outcome. This project focuses on eye gaze perception, the ability to accurately and efficiently discriminate others' gaze direction, as a potential biomarker of social functioning that cuts across psychiatric diagnoses. This premise builds on both the monkey and human literatures showing gaze perception as a basic building block supporting higher-level social communication and social development, and reports of abnormal gaze perception in multiple psychiatric conditions accompanied by prominent social dysfunction (e.g., psychosis-spectrum disorders, autism-spectrum disorders, social phobia). A large sample (

Indexed as

autism-spectrum disordersfunctional magnetic resonance imaginggaze perceptionpsychosissocial anxietysocial cognitionsocial functioning

Identifiers

PMID33072887
PMCPMC7566880
OpenAlexW3086134830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.