Evidence map›Paper›PMID 33072794›Full record

ReviewFrontiers in nutrition2020

The Pros and Cons of Using Algal Polysaccharides as Prebiotics.

Martin Gotteland, Karla Riveros, Naschla Gasaly, Constanza Carcamo, Fabien Magne, Gianella Liabeuf, Alejandra Beattie, Sebastián Rosenfeld

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Role ofNutrients · 2025
    Pooled it
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  6. Review
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  13. Foods (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin GottelandDepartment of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile.
Karla RiverosDepartment of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile.
Naschla GasalyDepartment of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile.
Constanza CarcamoDepartment of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile.
Fabien MagneMicrobiology and Mycology Program, Institute of Biomedical Sciences (ICBM), Faculty of Medicine, University of Chile, Santiago, Chile.
Gianella LiabeufDepartment of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile.
Alejandra BeattieLaboratorio de Ecosistemas Marinos Antárticos y Subantárticos, Universidad de Magallanes, Punta Arenas, Chile.
Sebastián RosenfeldLaboratorio de Ecosistemas Marinos Antárticos y Subantárticos, Universidad de Magallanes, Punta Arenas, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macroalgae stand out for their high content of dietary fiber (30-75%) that include soluble, sulfated (fucoidan, agaran, carrageenan, and ulvan) and non-sulfated (laminaran and alginate) polysaccharides. Many studies indicate that these compounds exert varied biological activities and health-promoting effects and for this reason, there is a growing interest for using them in food products. The aim of this review was to critically evaluate prebiotic properties of algal polysaccharides, i.e., their ability to exert biological activities by modulating the composition and/or diversity of gut microbiota (GM). Pre-clinical studies show that the non-sulfated alginate and laminaran are well-fermented by GM, promoting the formation of short chain fatty acids (SCFAs) including butyrate, and preventing that of harmful putrefactive compounds (NH

Indexed as

agaranalginatecarrageenanfucoidangut microbiotalaminaransulfated polysaccharidesulvan

Identifiers

PMID33072794
PMCPMC7536576

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.