Evidence map›Paper›PMID 33072770›Full record

ArticleFrontiers in medicine2020

The Double-Edged Sword of Immunosuppressive Therapy in Kidney Transplantation: A Rare Case Report of Pulmonary Mucormycosis Post-Transplant and Literature Review.

Hengcheng Zhang, Ke Wang, Hao Chen, Li Sun, Zijie Wang, Shuang Fei, Ruoyun Tan, Min Gu

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hengcheng ZhangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ke WangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hao ChenDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Li SunDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zijie WangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Shuang FeiDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ruoyun TanDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Min GuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunosuppressive therapy is improving the graft survival of kidney transplant recipients and increasing the potential risk of infection. Pulmonary mucormycosis is a rare post-operative infection complication characterized with rapid deterioration and high mortality. In this case, a 33-year-old patient underwent a kidney transplantation with regular immunosuppressive therapy. Soon, 38 days post-transplant, pulmonary patchy shadows can be seen in the radiological examination and rounded into a large cavity formation with splenic rupture 25 days later. The diagnosis of mucormycosis was confirmed by lung biopsy and spleen histopathology. This case is a reminder that early diagnosis is imperative, meanwhile, rational antifungal therapy, timely elimination of immunosuppressants, and alternatively, abandoning the graft should be prudently assessed in the treatment of mucormycosis.

Indexed as

case reportimmunosuppressantinfectionkidney transplantationmucormucormycosispulmonary

Identifiers

PMID33072770
PMCPMC7538690

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.