Evidence map›Paper›PMID 33072718›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Confocal Microscopy Improves 3D Microdosimetry Applied to Nanoporation Experiments Targeting Endoplasmic Reticulum.

Annalisa De Angelis, Agnese Denzi, Caterina Merla, Frank M Andre, Lluis M Mir, Francesca Apollonio, Micaela Liberti

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Electric field bridging-effect in electrified microfibrils' scaffolds.Frontiers in bioengineering and biotechnology · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Annalisa De AngelisInter University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB) at Department of Electronic Engineering and Telecommunications (DIET), University of Rome "La Sapienza", Rome, Italy.
Agnese DenziInter University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB) at Department of Electronic Engineering and Telecommunications (DIET), University of Rome "La Sapienza", Rome, Italy.
Caterina MerlaNational Italian Agency for Energy, New Technologies and Sustainable Economic Development - Department of Sustainability (ENEA, SSPT) - Division of Health Protection Technologies, Rome, Italy.
Frank M AndreUniversité Paris-Saclay, Institut Gustave Roussy, CNRS, Metabolic and Systemic Aspects of Oncogenesis, Villejuif, France.
Lluis M MirUniversité Paris-Saclay, Institut Gustave Roussy, CNRS, Metabolic and Systemic Aspects of Oncogenesis, Villejuif, France.
Francesca ApollonioInter University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB) at Department of Electronic Engineering and Telecommunications (DIET), University of Rome "La Sapienza", Rome, Italy.
Micaela LibertiInter University Center for the Study of Electromagnetic Fields and Biological Systems (ICEmB) at Department of Electronic Engineering and Telecommunications (DIET), University of Rome "La Sapienza", Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last years, microdosimetric numerical models of cells including intracellular compartments have been proposed, aiming to investigate the poration induced by the application of nanosecond pulsed electric fields (nsPEFs). A limitation of such models was the extremely approximate cell and organelle shapes, leading to an incorrect estimation of the electric field or transmembrane potential distribution in the studied domain. In order to obtain a reliable model of

Indexed as

confocal fluorescence microscopyelectropermeabilizationelectroporationendoplasmic reticulummicrodosimetrynanoporation experimentsnanosecond pulsesrealistically shaped cell models

Identifiers

PMID33072718
PMCPMC7537786

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.