Evidence map›Paper›PMID 33072656›Full record

ReviewClinical and translational imaging2020

Value of chest computed tomography scan in diagnosis of COVID-19; a systematic review and meta-analysis.

Hasti Hossein, Kosar Mohamed Ali, Mostafa Hosseini, Arash Sarveazad, Saeed Safari, Mahmoud Yousefifard

Abstract readReview
In one paragraph

Review in Clinical and translational imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Contribution ofCurrent issues in molecular biology · 2025
    Review
  3. Article
  4. Article
  5. COVID-19 diagnostics: Molecular biology to nanomaterials.Clinica chimica acta; international journal of clinical chemistry · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  17. Review
  18. Characteristics and outcomes of hospital admissions for COVID-19 and influenza in the Toronto area.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  19. Article
  20. Antigen tests for COVID-19.Biophysics and physicobiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hasti HosseinPhysiology Research Center, Iran University of Medical Sciences, Hemmat highway, Tehran, Iran.
Kosar Mohamed AliCollege of Medicine, University of Sulaimani, Sulaimani, Iraq.
Mostafa HosseiniDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Arash SarveazadColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Saeed SafariProteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mahmoud YousefifardPhysiology Research Center, Iran University of Medical Sciences, Hemmat highway, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeReal-time polymerase chain reaction (RT-PCR) and chest computed tomography (CT) scan are main diagnostic modalities of coronavirus disease 2019 (COVID-19). However, there is still no consensus on which of these methods is superior to the other. Therefore, the present meta-analysis was designed to answer to the question whether CT scan can be used in diagnosis of COVID-19 or not.

methodsSearches were performed in Medline, Embase, Scopus, and Web of Science databases until the end of April 2020. Two researchers gathered the data of diagnostic accuracy studies that had attempted to evaluate sensitivity and specificity of CT scan in diagnosis of COVID-19.

resultsData of 9 studies were included. Area under the curve of ground glass opacity (GGO), consolidation, pleural effusion, other CT features, and simultaneous observation of GGO with other CT features was 0.64 (95% CI 0.60-0.69), 0.30 (95% CI 0.26-0.34), 0.60 (95% CI 0.56-0.64), 0.61 (95% CI 0.56-0.65), and 0.90 (95% CI 0.87-0.92), respectively. Sensitivity and specificity of simultaneous observation of GGO with other CT scan features was higher than all of the other signs. Sensitivity, specificity, and diagnostic odds ratio of this sign was calculated to be 0.90, 0.89, and 20, respectively.

conclusionSimultaneous observation of GGO and other features of viral pneumonia in CT scan had optimum performance in detection of COVID-19. However, it is suggested to make the final diagnosis based on both CT scan and RT-PCR, as none of the two diagnostic modalities are reliable alone.

Indexed as

COVID-19Polymerase chain reactionSevere acute respiratory syndrome coronavirus 2Tomography X-ray computed

Identifiers

PMID33072656
PMCPMC7549426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.