Evidence map›Paper›PMID 33072606›Full record

ArticleFrontiers in oncology2020

A Competing Risk Analysis Model to Determine the Prognostic Value of Isolated Tumor Cells in Axillary Lymph Nodes for T1N0M0 Breast Cancer Patients Based on the Surveillance, Epidemiology, and End Results Database.

Yijun Li, Huimin Zhang, Wei Zhang, Yu Ren, Yan Qiao, Kunlong Li, Heyan Chen, Shengyu Pu, Jianjun He, Can Zhou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yijun LiDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Huimin ZhangDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wei ZhangDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yu RenDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yan QiaoDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Kunlong LiDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Heyan ChenDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Shengyu PuDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jianjun HeDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Can ZhouDepartment of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
First Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKnowledge of the association between isolated tumor cells (ITCs) in breast cancer patients and the outcome is very limited. We aimed to determine the prognostic value of axillary lymph node ITCs for T1N0M0 female breast cancer (FBC) patients.

methodsData for T1N0M0 FBC patients staged ITCs negative [pN0(i-)] and positive [pN0(i+)] were extracted from the Surveillance, Epidemiology, and End Results database from 2004 to 2015. Prognostic predictors were identified by Kaplan-Meier analysis, competing risk model, and Fine-Gray multivariable regression model.

resultsA total of 94,599 subjects were included, 88,632 of whom were staged at pN0(i-) and 5,967 were pN0(i+). Patients staged pN0(i+) had worse breast cancer-specific survival (BCSS) [hazard ratio (HR): 1.298, 95% CI = 1.069-1.576,

conclusionITC was independently related to the increase of the BCSD rate and could be identified as a reliable survival predictor for T1N0M0 FBC patients.

Indexed as

competing risk modelfemale breast cancerisolated tumor cellsSEER databasesurvival analysis

Identifiers

PMID33072606
PMCPMC7531361
OpenAlexW3088926300

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.