Evidence map›Paper›PMID 33072434›Full record

ArticlePeerJ2020

Effects of early life stage exposure of largemouth bass to atrazine or a model estrogen (17α-ethinylestradiol).

Jessica K Leet, Catherine A Richter, Robert S Cornman, Jason P Berninger, Ramji K Bhandari, Diane K Nicks, James L Zajicek, Vicki S Blazer, Donald E Tillitt

Abstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jessica K LeetColumbia Environmental Research Center, United States Geological Survey, Columbia, MO, USA.ORCID 0000-0001-8142-6043
Catherine A RichterColumbia Environmental Research Center, United States Geological Survey, Columbia, MO, USA.
Robert S CornmanFort Collins Science Center, United States Geological Survey, Fort Collins, CO, USA.ORCID 0000-0001-9511-2192
Jason P BerningerColumbia Environmental Research Center, United States Geological Survey, Columbia, MO, USA.
Ramji K BhandariDepartment of Biology, University of North Carolina at Greensboro, Greensboro, NC, USA.
Diane K NicksColumbia Environmental Research Center, United States Geological Survey, Columbia, MO, USA.
James L ZajicekColumbia Environmental Research Center, United States Geological Survey, Columbia, MO, USA.
Vicki S BlazerLeetown Science Center, United States Geological Survey, Kearneysville, WV, USA.ORCID 0000-0001-6647-9614
Donald E TillittColumbia Environmental Research Center, United States Geological Survey, Columbia, MO, USA.ORCID 0000-0002-8278-3955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine disrupting contaminants are of continuing concern for potentially contributing to reproductive dysfunction in largemouth and smallmouth bass in the Chesapeake Bay watershed (CBW) and elsewhere. Exposures to atrazine (ATR) have been hypothesized to have estrogenic effects on vertebrate endocrine systems. The incidence of intersex in male smallmouth bass from some regions of CBW has been correlated with ATR concentrations in water. Fish early life stages may be particularly vulnerable to ATR exposure in agricultural areas, as a spring influx of pesticides coincides with spawning and early development. Our objectives were to investigate the effects of early life stage exposure to ATR or the model estrogen 17α-ethinylestradiol (EE2) on sexual differentiation and gene expression in gonad tissue. We exposed newly hatched largemouth bass (LMB,

Indexed as

AtrazineEndocrine disrupting contaminantsEthinylestradiolFishGene expressionGonad developmentRNAseq

Identifiers

PMID33072434
PMCPMC7537618

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.