ArticleTurkish journal of obstetrics and gynecology2020
Pregnancy worsens the morbidity of COVID-19 and this effect becomes more prominent as pregnancy advances.
Article in Turkish journal of obstetrics and gynecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss.Human reproduction update · 2024Pooled it
- The association between pregnancy and COVID-19: A systematic review and meta-analysis.The American journal of emergency medicine · 2022Pooled it
- Comparison of the clinical outcomes of COVID-19 in pregnant and non-pregnant patients of reproductive age.European journal of medical research · 2025Article
- Pathological Examination of the Placenta in COVID-19-Positive Mothers: A Short Communication.Iranian journal of pathology · 2023Article
- Association of Pregnancy With Coronavirus Cytokine Storm: Systematic Review and Meta-analysis.JMIR pediatrics and parenting · 2022Review
- COVID-19 disease and vaccination in pregnant and lactating women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022Review
- COVID-19 related maternal mortality cases in associated with Delta and Omicron waves and the role of lung ultrasound.Turkish journal of obstetrics and gynecology · 2022Article
- Effects of SARS-CoV-2 Variants on Maternal Infection and Severity: A Single-Center Experience.Cureus · 2022Article
- Vitamin D status is not associated with clinical severity of COVID-19 in pregnant women.European journal of nutrition · 2022Article
- An internally validated prediction model for critical COVID-19 infection and intensive care unit admission in symptomatic pregnant women.American journal of obstetrics and gynecology · 2022Article
- Pregnant and Postpartum Women Requiring Intensive Care Treatment for COVID-19-First Data from the CRONOS-Registry.Journal of clinical medicine · 2022Article
- Clinical evaluation of pregnant women with SARS-COV2 pneumonia: a real-life study from Egypt.The Journal of the Egyptian Public Health Association · 2021Article
- Maternal deaths due to COVID-19 disease: The cases in a single center pandemic hospital in the south east of Turkey.The journal of obstetrics and gynaecology research · 2021Article
- Clinical and radiologic characteristics of symptomatic pregnant women with COVID-19 pneumoniaJournal of the Turkish German Gynecological Association · 2021Article
- Knowledge, Attitude and Practice Toward Corona virus Infection Among Pregnant Women Attending Antenatal Care at Public Hospitals in Three Wollega Zones, Ethiopia.International journal of general medicine · 2021Article
- SARS-CoV-2 in Pregnancy: Fitting Into the Existing Viral Repertoire.Frontiers in global women's health · 2021Review
- Corticosteroids Use in Pregnant Women with COVID-19: Recommendations from Available Evidence.Journal of multidisciplinary healthcare · 2021Article
- A Comprehensive Analysis of Maternal and Newborn Disease and Related Control for COVID-19.SN comprehensive clinical medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate pregnancy outcomes and compare the clinical characteristics of coronavirus 2019 (COVID-19) disease in pregnant and agematched non-pregnant women. MATERIALS AND
methodsHospital records of four tertiary care centers were reviewed retrospectively. The subjects comprised 188 pregnant patients and 799 non-pregnant women who were admitted to these hospitals.
resultsPregnancy significantly affected the clinical severity of COVID-19 and this effect was more prominent in pregnant women at >20 weeks gestation (p<0.001). Rates of oxygen support (10.1% vs 4.8%; p≤0.001), intensive care unit admission (3.2% vs 0.6%; p=0.009), presence of fever (12.8% vs 4.4%; p<0.001), tachypnea (7.0% vs 2.4%; p=0.003) and tachycardia (16.0% vs 1.9%; p<0.001) were significantly more frequent in pregnant women compared with non-pregnant women. Pregnancy was strongly associated with the need for oxygen support [relative risk (RR), 2.125; 95% confidence interval (CI): 1.25-3.60] and admission to the intensive care unit (RR, 5.1; 95% CI: 1.57-16.53) compared with non-pregnant women. Some 14.4% of the pregnant women had co-morbidities. Sixty of the 188 pregnant women (31.9%) delivered during the Severe Acute Respiratory syndrome coronavirus-2 infection, 11 (18.3%) had vaginal deliveries and 49 (81.7%) were by cesarean section. Of these 60 deliveries, 40 (66.7%) were <37 weeks gestation.
conclusionPregnancy worsens the morbidity of COVID-19 and this effect seems to increase as the pregnancy advances, but not the mortality rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.