ReviewEFORT open reviews2020
Literature review of the causes of pain following total knee replacement surgery: prosthesis, inflammation and arthrofibrosis.
Review in EFORT open reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Early Clinical and Radiographic Outcomes of Robot-Assisted Versus Conventional Manual Total Knee Arthroplasty: A Randomized Controlled Study.Orthopaedic surgery · 2022Trial
- Chronic Pain and Stiffness After Total Knee Arthroplasty: A Comprehensive, Phenotype-Based Review of Mechanisms, Diagnosis and Management.Journal of clinical medicine · 2026Review
- Corrosion and wear damage estimations for retrieved knee and hip implants.Npj Materials degradation · 2026Article
- Robotic-Assisted Total Knee Arthroplasty in HIV-Positive Patients: Precision Surgery for a Changing Epidemic.Orthopedic reviews · 2026Article
- Phenomenological exploration of experiences, satisfaction and quality of life after 1-month total knee arthroplasty rehabilitation: "pain decreased; discomfort disappeared".Scientific reports · 2025Article
- Evaluation of neuropathic-like symptoms and objective signs of neuropathy post-knee replacement in patients with knee osteoarthritis.Osteoarthritis and cartilage open · 2025Article
- [Effectiveness and safety analysis of simultaneous bilateral total knee arthroplasty in treatment of patients aged 65 years and younger with bilateral knee osteoarthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Improvement in Central Sensitization Following Total Knee Arthroplasty Is Associated With Severe Preoperative Pain and Affects Postoperative Quality of Life: A Retrospective Study.Orthopaedic surgery · 2025Article
- New-onset obstructive sleep apnea and insomnia after total knee replacement in patients with osteoarthritis: real-world evidences.Therapeutic advances in musculoskeletal disease · 2025Article
- Biopsychosocial Determinants for Total Knee Replacement Decisions Among Older Adults With Chronic Knee Osteoarthritis: A Scoping Review.Geriatric orthopaedic surgery & rehabilitation · 2025Review
- Conversion of Unicompartmental Knee Arthroplasty to Total Knee Arthroplasty for Cement Allergy.Arthroplasty today · 2024Article
- The Optimal Variation Range of Posterior Condylar Offset Associated with Positive Clinical Outcomes of Primary Total Knee Arthroplasty: A Retrospective Analysis.Orthopaedic surgery · 2024Article
- Herpes Zoster Risk After Total Knee Replacement: a multicenter, propensity-score-matched cohort study in the United States.International journal of medical sciences · 2024Article
- Severe Postoperative Pain in Total Knee Arthroplasty Patients: Risk Factors, Insights and Implications for Pain Management via a Digital Health Approach.Journal of clinical medicine · 2023Article
- Mismatch between trochlear coronal alignment of arthritic knees and currently available prosthesis: a morphological analysis of 4116 knees and 45 implant designs.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Thyroid Diseases After Total Knee Replacement: A Multi-center, Propensity-score-matched Cohort Study.In vivo (Athens, Greece)Article
- New-onset Fibromyalgia After Total Knee Replacement in Patients With Osteoarthritis: A Propensity-score-matched Cohort Study in the United States.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adverse knee pain occurs in 10-34% of all total knee replacements (TKR), and 20% of TKR patients experience more pain post-operatively than pre-operatively. Knee pain is amongst the top five reasons for knee replacement revision in the United Kingdom. The number of TKRs is predicted to continue increasing due to the ageing population.A narrative literature review was performed on the different causes of pain following TKR. A database search on Scopus, PubMed, and Google Scholar was conducted to look for articles related to TKR, pain, and cause. Articles were selected based on relevance, publication date, quality of research and validation. Relevant sections were added to the review.One hundred and fourteen articles were identified and potential causes of TKR pain included: arthrofibrosis, aseptic loosening, avascular necrosis, central sensitization, component malpositioning, infection, instability, nerve damage, overstuffing, patellar maltracking, polyethylene wear, psychological factors and unresurfaced patella.It is important to tailor our approach to address the individual causes of pain. Certain controllable risk factors can be managed pre-operatively to minimize post-operative pain. Risk factors help to predict adverse pain outcomes and identify specific causes.There are multiple causes of pain following TKR. Some factors will require further extensive studies, and as pain is a commonly attributed reason for TKR revision, its underlying aetiologies should be explored. Understanding these factors helps to develop effective methods for diagnosis, prevention and management of TKR pain, which help to improve patient outcomes. Cite this article:
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