Evidence map›Paper›PMID 33072392›Full record

ArticleAsthma research and practice2020

Non-adherence to inhaled medications among adult asthmatic patients in Ethiopia: a systematic review and meta-analysis.

Woldu Aberhe, Abrha Hailay, Kidane Zereabruk, Guesh Mebrahtom, Teklehaimanot Haile

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Article in Asthma research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

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13citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Woldu AberheDepartment of Adult Health Nursing, School of Nursing, Aksum University, Aksum, Ethiopia.
Abrha HailayDepartment of Adult Health Nursing, School of Nursing, Aksum University, Aksum, Ethiopia.
Kidane ZereabrukDepartment of Adult Health Nursing, School of Nursing, Aksum University, Aksum, Ethiopia.
Guesh MebrahtomDepartment of Adult Health Nursing, School of Nursing, Aksum University, Aksum, Ethiopia.
Teklehaimanot HaileDepartment of Maternity and Neonatal Nursing, School of Nursing, Aksum University, Aksum, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedication non-adherence is one of a common problem in asthma management and it is the main factor for uncontrolled asthma. It can result in poor asthma control, which leads to decreased quality of life, increase hospital admission, increased health care utilization, lost productivity, and mortality. To date, there have been no studies and protocols that estimated the pooled national prevalence of non-adherence to inhaled anti-asthmatic medications in Ethiopia. Therefore, the primary purpose of this systematic review and meta-analysis is to determine the pooled national prevalence of non-adherence to inhaled medications among asthmatic patients in Ethiopia.

methodsDifferent database searching engines including PubMed, Scopus, Google Scholar, Africa journal online, World Health Organization afro library, and Cochrane review were systematically searched by using keywords such as "prevalence, non-adherence to inhaled medications, inhaled corticosteroids, and asthmatic patients" and their combinations. Six published observational studies that report the prevalence of non-adherence to inhaled medications were finally selected. The Preferred Reporting Items for Systematic Review and Meta-Analysis guideline was followed. Heterogeneity across the included studies was evaluated by the inconsistency index (I

resultsThe pooled national prevalence of non-adherence to inhaled medications among asthmatic patients was 29.95% (95% CI, 19.1, 40.8%). The result of this meta-analysis using the random-effects model revealed that there is high heterogeneity across the included studies. The result of subgroup analysis indicates that one out of three in the Oromia region and one out of five in the Amhara region asthmatic patients was non-adherent to their inhaled anti-asthmatic medications.

conclusionthe prevalence of non-adherence to inhaled anti-asthmatic medications was high. Thus, our finding suggests that one out of four asthmatic patients were non-adherent to inhaled medications. The ministry of health, health policymakers, clinicians, and other health care providers should pay attention to strengthening the adherence levels to inhaled anti-asthmatic medications, and country-based interventions should be developed to reduce the burden of non-adherence to inhaled anti-asthmatic medications.

Indexed as

And prevalenceAsthmaEthiopiaMedications non-adherenceMeta-analysis

Identifiers

PMID33072392
PMCPMC7556918

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.