Evidence map›Paper›PMID 33072254›Full record

ArticleJournal of surgical case reports2020

ACE inhibitor-induced small bowel angioedema, mimicking an acute abdomen.

Rafaela Parreira, Rui Amaral, Luís Amaral, Teresa Elói, Maria Inês Leite, Armando Medeiros

Erratum issuedOpen access · goldAbstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rafaela ParreiraGeneral Surgery Department, Hospital do Divino Espírito Santo, EPE, Ponta Delgada, Portugal.
Rui AmaralImagiology Department, Hospital do Divino Espírito Santo, EPE, Ponta Delgada, Portugal.
Luís AmaralGeneral Surgery Department, Hospital do Divino Espírito Santo, EPE, Ponta Delgada, Portugal.
Teresa ElóiGeneral Surgery Department, Hospital do Divino Espírito Santo, EPE, Ponta Delgada, Portugal.
Maria Inês LeiteGeneral Surgery Department, Hospital do Divino Espírito Santo, EPE, Ponta Delgada, Portugal.
Armando MedeirosGeneral Surgery Department, Hospital do Divino Espírito Santo, EPE, Ponta Delgada, Portugal.
Hospital do Divino Espírito Santo · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiotensin-converting enzyme (ACE) inhibitors are the leading cause of drug-induced angioedema, being the face, tongue, lips and upper airway the most affected ones. We describe a case of a 32-year-old white female with angioedema of small intestine after 1 month of perindopril therapy. The patient presented severe abdominal pain, nausea and vomiting. Laboratory analyses revealed mild leukocytosis and abdominal computed tomography (CT) showed unspecific findings, including segmental jejunal wall thickening without obstruction and ascites. Regarding the clinical findings, similar to an acute abdomen with no clear cause, the patient underwent an emergency laparoscopy that excluded other pathological features. The symptoms recurred 1 month after and the CT scan revealed the same pattern. Perindopril was stopped and the patient improved, concluding that ACE inhibitor-induced visceral angioedema was responsible for this clinical presentation.

Identifiers

PMID33072254
PMCPMC7546248
OpenAlexW3091955366

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.