Evidence map›Paper›PMID 33072236›Full record

ArticleThe annals of applied statistics2019

A SEMIPARAMETRIC MODELING APPROACH USING BAYESIAN ADDITIVE REGRESSION TREES WITH AN APPLICATION TO EVALUATE HETEROGENEOUS TREATMENT EFFECTS.

Bret Zeldow, Vincent Lo Re, Jason Roy

Open access · bronzeAbstract read
In one paragraph

Article in The annals of applied statistics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bret ZeldowDepartment of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, Massachusetts 02115, USA.
Vincent Lo ReDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Jason RoyDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey 08854, USA.
Rutgers, The State University of New Jersey · USUniversity of Pennsylvania · US

Funding

Non-Parametric Bayesian Methods for Causal InferenceR01GM112327 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ROY, JASON A · 2014 to 2017
$1.4M
NIGMS NIH HHS R01 GM112327
6 · The paper itself

Abstract

Bayesian Additive Regression Trees (BART) is a flexible machine learning algorithm capable of capturing nonlinearities between an outcome and covariates and interactions among covariates. We extend BART to a semiparametric regression framework in which the conditional expectation of an outcome is a function of treatment, its effect modifiers, and confounders. The confounders are allowed to have unspecified functional form, while treatment and effect modifiers that are directly related to the research question are given a linear form. The result is a Bayesian semiparametric linear regression model where the posterior distribution of the parameters of the linear part can be interpreted as in parametric Bayesian regression. This is useful in situations where a subset of the variables are of substantive interest and the others are nuisance variables that we would like to control for. An example of this occurs in causal modeling with the structural mean model (SMM). Under certain causal assumptions, our method can be used as a Bayesian SMM. Our methods are demonstrated with simulation studies and an application to dataset involving adults with HIV/Hepatitis C coinfection who newly initiate antiretroviral therapy. The methods are available in an R package called semibart.

Indexed as

antiretroviralsBayesian Additive Regression Treesstructural mean model

Identifiers

PMID33072236
PMCPMC7566884
OpenAlexW2807994798

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.