Evidence map›Paper›PMID 33072047›Full record

ArticleFrontiers in microbiology2020

A Novel, Orally Delivered Antibody Therapy and Its Potential to Prevent

April K Roberts, Hannah C Harris, Michael Smith, Joanna Giles, Oktawia Polak, Anthony M Buckley, Emma Clark, Duncan Ewin, Ines B Moura, William Spitall and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Mechanisms ofFrontiers in cellular and infection microbiology · 2025
    Review
  2. Article
  3. Immunization Strategies Against Clostridioides difficile.Advances in experimental medicine and biology · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Application of Microbiome Management in Therapy forPathogens (Basel, Switzerland) · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

April K RobertsToxins Group, National Infection Service, Public Health England, Porton Down, United Kingdom.
Hannah C HarrisLeeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
Michael SmithToxins Group, National Infection Service, Public Health England, Porton Down, United Kingdom.
Joanna GilesMicroPharm Ltd., Newcastle Emlyn, United Kingdom.
Oktawia PolakMicroPharm Ltd., Newcastle Emlyn, United Kingdom.
Anthony M BuckleyLeeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
Emma ClarkLeeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
Duncan EwinLeeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
Ines B MouraLeeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
William SpitallLeeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
Clifford C ShoneToxins Group, National Infection Service, Public Health England, Porton Down, United Kingdom.
Mark WilcoxLeeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
Caroline ChiltonLeeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
Rossen DonevMicroPharm Ltd., Newcastle Emlyn, United Kingdom.
University of Leeds · GBPublic Health England · GB

Funding

Medical Research Council MC_PC_14092
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clostridioides difficile infection (CDI)formulation protecting antibodies from digestion/inactivationimmunotherapy of CDIin vitro human gut model of CDIin vivo hamster model of CDIoral antibodies

Identifiers

PMID33072047
PMCPMC7537341
OpenAlexW3088348837

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.