Evidence map›Paper›PMID 33071975›Full record

ReviewFrontiers in endocrinology2020

Quantitative Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of Bone: An Update.

Ya-Jun Ma, Saeed Jerban, Hyungseok Jang, Douglas Chang, Eric Y Chang, Jiang Du

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Fast 3D UTE in vivo TMagnetic resonance in medicine · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. QuantitativeJournal of magnetic resonance imaging : JMRI · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Ultrashort echo time MRI detects significantly lower collagen but higher pore water in the tibial cortex of female patients with osteopenia and osteoporosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ya-Jun MaDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Saeed JerbanDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Hyungseok JangDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Douglas ChangDepartment of Orthopedic Surgery, University of California, San Diego, San Diego, CA, United States.
Eric Y ChangDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Jiang DuDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.

Funding

Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of BoneR01AR068987 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2024
$4.9M
Quantitative UTE MR Imaging: Sensitive Biomarkers for OsteoarthritisR01AR062581 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2013 to 2022
$4.1M
Three-dimensional Ultrashort Echo Time Magnetic Resonance Imaging of EnthesesR01AR075825 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI CHANG, ERIC Y · 2019 to 2023
$1.8M
Three-Dimensional UTE Magnetic Resonance Imaging of the Osteochondral JunctionR21AR075851 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MA, YAJUN · 2020 to 2021
$376k
Ultrashort Echo Time Magnetic Resonance Imaging of Bone Stress InjuriesR21AR073496 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI CHANG, ERIC Y · 2018 to 2019
$343k
Quantitative Measurement of Joint pH with Magnetic Resonance ImagingI01RX002604 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2018 to 2022
–
Quantitative Magnetic Resonance Imaging of Human Rotator Cuff TendonI01CX001388 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2016 to 2024
–
CSRD VA I01 CX001388NIAMS NIH HHS R01 AR062581NIAMS NIH HHS R01 AR068987NIAMS NIH HHS R01 AR075825NIAMS NIH HHS R21 AR073496NIAMS NIH HHS R21 AR075851RRD VA I01 RX002604
6 · The paper itself

Abstract

Bone possesses a highly complex hierarchical structure comprised of mineral (~45% by volume), organic matrix (~35%) and water (~20%). Water exists in bone in two forms: as bound water (BW), which is bound to bone mineral and organic matrix, or as pore water (PW), which resides in Haversian canals as well as in lacunae and canaliculi. Magnetic resonance (MR) imaging has been increasingly used for assessment of cortical and trabecular bone. However, bone appears as a signal void on conventional MR sequences because of its short T2

Indexed as

AnimalsBone DensityCortical BoneEcho-Planar ImagingHumansMagnetic Resonance ImagingTime FactorsWaterX-Ray MicrotomographyWaterbone mineral densitycortical bonemacromolecular fractionMRItrabecular boneUTEwater contents

Identifiers

PMID33071975
PMCPMC7531487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.