Evidence map›Paper›PMID 33071830›Full record

ArticleFrontiers in physiology2020

Identification of Novel SCN5A Single Nucleotide Variants in Brugada Syndrome: A Territory-Wide Study From Hong Kong.

Gary Tse, Sharen Lee, Tong Liu, Ho Chuen Yuen, Ian Chi Kei Wong, Chloe Mak, Ngai Shing Mok, Wing Tak Wong

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Risk stratification of sudden cardiac death in asymptomatic female Brugada syndrome patients: A literature review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Gary TseXiamen Cardiovascular Hospital, Xiamen University, Xiamen, China.
Sharen LeeLaboratory of Cardiovascular Physiology, Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.
Ho Chuen YuenDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Kowloon, China.
Ian Chi Kei WongCentre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, China.
Chloe MakDepartment of Pathology, Hong Kong Children's Hospital, Kowloon, China.
Ngai Shing MokDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Kowloon, China.
Wing Tak WongState Key Laboratory of Agrobiotechnology (CUHK), School of Life Sciences, The Chinese University of Hong Kong, Shatin, China.
Kowloon Hospital · CNChinese University of Hong Kong · CNFirst Affiliated Hospital of Xiamen University · CNTianjin Medical University · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study is to report on the genetic composition of Brugada syndrome (BrS) patients undergoing genetic testing in Hong Kong.

methodsPatients with suspected BrS who presented to the Hospital Authority of Hong Kong between 1997 and 2019, and underwent genetic testing, were analyzed retrospectively.

resultsA total of 65 subjects were included (

conclusionThis study identified novel mutations in SCN5A in a Chinese cohort of BrS patients.

Indexed as

Brugada syndromerisk stratificationSCN5ASudden cardiac deathventricular arrhythmias

Identifiers

PMID33071830
PMCPMC7531256
OpenAlexW3087251718

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.