Evidence map›Paper›PMID 33071820›Full record

ArticleFrontiers in physiology2020

Treatment With Gemfibrozil Prevents the Progression of Chronic Kidney Disease in Obese Dahl Salt-Sensitive Rats.

Corbin A Shields, Bibek Poudel, Kasi C McPherson, Andrea K Brown, Ubong S Ekperikpe, Evan Browning, Lamari Sutton, Denise C Cornelius, Jan M Williams

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Corbin A ShieldsDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
Bibek PoudelDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
Kasi C McPhersonDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
Andrea K BrownDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
Ubong S EkperikpeDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
Evan BrowningDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
Lamari SuttonDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
Denise C CorneliusDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
Jan M WilliamsDepartment of Experimental Therapeutics and Pharmacology, University of Mississippi Medical Center, Jackson, MS, United States.
University of Mississippi Medical Center · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI Jennifer L Lemacks · 2012 to 2026
$60.2M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Pier Paolo Claudio, Babbette LaMarca · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, JOHN E · 2013 to 2022
$23.4M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Hypertension, Inflammation, and Vascular FunctionR01HL151407 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2020 to 2024
$1.9M
Mechanisms involved in the early development of renal disease associated with prepubertal obesityR01DK109133 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI WILLIAMS, JAN MICHAEL · 2017 to 2021
$1.7M
Hypertension and InflammationR00HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2017 to 2019
$747k
Hypertension and InflammationK99HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2016 to 2016
$136k
NHLBI NIH HHS K99 HL130456NHLBI NIH HHS R00 HL130456NHLBI NIH HHS R01 HL151407NHLBI NIH HHS T32 HL105324NIDDK NIH HHS R01 DK109133NIGMS NIH HHS P20 GM103476NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

Recently, we reported that Dahl salt-sensitive leptin receptor mutant (SS

Indexed as

gemfibrozillipid accumulationobesityrenal injurySSLepRmutant ratSS rat

Identifiers

PMID33071820
PMCPMC7533555
OpenAlexW3087027413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.