Evidence map›Paper›PMID 33071775›Full record

ReviewFrontiers in pharmacology2020

Response to the Novel Corona Virus (COVID-19) Pandemic Across Africa: Successes, Challenges, and Implications for the Future.

Olayinka O Ogunleye, Debashis Basu, Debjani Mueller, Jacqueline Sneddon, R Andrew Seaton, Adesola F Yinka-Ogunleye, Joshua Wamboga, Nenad Miljković, Julius C Mwita, Godfrey Mutashambara Rwegerera and 62 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 4 syntheses or guidelines pooled it, 214 citations in OpenAlex.

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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

72 authors at 20 institutions in 25 countries.

Olayinka O OgunleyeDepartment of Pharmacology, Therapeutics and Toxicology, Lagos State University College of Medicine, Lagos, Nigeria.
Debashis BasuDepartment of Public Health Medicine, Steve Biko Academic Hospital and the University of Pretoria, Pretoria, South Africa.
Debjani MuellerCharlotte Maxeke Medical Research Cluster, Johannesburg, South Africa.
Jacqueline SneddonHealthcare Improvement Scotland, Glasgow, United Kingdom.
R Andrew SeatonHealthcare Improvement Scotland, Glasgow, United Kingdom.
Adesola F Yinka-OgunleyeDepartment of Surveillance and Epidemiology, Nigerian Centre for Disease Control, Abuja, Nigeria.
Joshua WambogaUganda Alliance of Patients' Organizations (UAPO), Kampala, Uganda.
Nenad MiljkovićInstitute of Orthopaedic Surgery "Banjica", University of Belgrade, Belgrade, Serbia.
Julius C MwitaDepartment of Internal Medicine, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Godfrey Mutashambara RwegereraDepartment of Internal Medicine, University of Botswana and Department of Medicine, Princess Marina Hospital, Gaborone, Botswana.
Amos MasseleDepartment of Biomedical Sciences, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Okwen PatrickEffective Basic Services (eBASE) Africa, Bamenda, Cameroon.
Loveline Lum NibaEffective Basic Services (eBASE) Africa, Bamenda, Cameroon.
Melaine NsaikilaEffective Basic Services (eBASE) Africa, Bamenda, Cameroon.
Wafaa M RashedChildren's Cancer Hospital, Cairo, Egypt.
Mohamed Ali HusseinChildren's Cancer Hospital, Cairo, Egypt.
Rehab HegazyPharmacology Department, Medical Division, National Research Centre, Giza, Egypt.
Adefolarin A AmuPharmacy Department, Eswatini Medical Christian University, Mbabane, Eswatini.
Baffour Boaten Boahen-BoatenDepartment of Psychology, Eswatini Medical Christian University, Mbabane, Eswatini.
Zinhle MatsebulaRaleigh Fitkin Memorial Hospital, Manzini, Eswatini.
Prudence GwebuRaleigh Fitkin Memorial Hospital, Manzini, Eswatini.
Bongani ChirigoRaleigh Fitkin Memorial Hospital, Manzini, Eswatini.
Nongabisa MkhabelaRaleigh Fitkin Memorial Hospital, Manzini, Eswatini.
Tenelisiwe DlaminiRaleigh Fitkin Memorial Hospital, Manzini, Eswatini.
Siphiwe SitholeRaleigh Fitkin Memorial Hospital, Manzini, Eswatini.
Sandile MalazaRaleigh Fitkin Memorial Hospital, Manzini, Eswatini.
Sikhumbuzo DlaminiRaleigh Fitkin Memorial Hospital, Manzini, Eswatini.
Daniel AfriyiePharmacy Department, Ghana Police Hospital, Accra, Ghana.
George Awuku AsareDepartment of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, Ghana.
Seth Kwabena AmponsahDepartment of Medical Pharmacology, University of Ghana Medical School, Accra, Ghana.
Israel SefahGhana Health Service, Pharmacy Department, Keta Municipal Hospital, Keta-Dzelukope, Ghana.
Margaret OlukaDepartment of Pharmacology and Pharmacognosy, School of Pharmacy, University of Nairobi, Nairobi, Kenya.
Anastasia N GuantaiDepartment of Pharmacology and Pharmacognosy, School of Pharmacy, University of Nairobi, Nairobi, Kenya.
Sylvia A OpangaDepartment of Pharmaceutics and Pharmacy Practice, School of Pharmacy, University of Nairobi, Nairobi, Kenya.
Tebello Violet SareleDiscipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Westville-campus, Durban, South Africa.
Refeletse Keabetsoe MafisaIndependent Researcher, Mafeteng, Lesotho.
Ibrahim ChikowePharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi.
Felix KhuluzaPharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi.
Dan KibuuleDepartment of Pharmacy Practice and Policy, Faculty of Health Sciences, University of Namibia, Windhoek, Namibia.
Francis KalemeeraDepartment of Pharmacy Practice and Policy, Faculty of Health Sciences, University of Namibia, Windhoek, Namibia.
Mwangana MubitaDepartment of Pharmacy Practice and Policy, Faculty of Health Sciences, University of Namibia, Windhoek, Namibia.
Joseph FadareDepartment of Pharmacology and Therapeutics, Ekiti State University , Ado-Ekiti, Nigeria.
Laurien SibomanaDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States.
Gwendoline Malegwale RamokgopaDepartment of Public Health Medicine, Steve Biko Academic Hospital and the University of Pretoria, Pretoria, South Africa.
Carmen WhyteDepartment of Public Health Medicine, Steve Biko Academic Hospital and the University of Pretoria, Pretoria, South Africa.
Tshegofatso MaimelaDepartment of Public Health Medicine, Steve Biko Academic Hospital and the University of Pretoria, Pretoria, South Africa.
Johannes HugoWHO Collaborating Centre for Social Determinants of Health and Health in all Policies, Pretoria, South Africa.
Johanna C MeyerSchool of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Natalie SchellackSchool of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Enos M RampambaSchool of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Adel VisserEugene Marais Hospital, Pretoria, South Africa.
Abubakr AlfadlNational Medicines Board, Federal Ministry of Health, Khartoum, Sudan.
Elfatih M MalikFaculty of Medicine, University of Khartoum, Khartoum, Sudan.
Oliver Ombeva MalandeDepartment of Child Health and Paediatrics, Egerton University, Nakuru, Kenya.
Aubrey C KalungiaDepartment of Pharmacy, University of Zambia, Lusaka, Zambia.
Chiluba MwilaDepartment of Pharmacy, University of Zambia, Lusaka, Zambia.
Trust ZaranyikaDepartment of Medicine, University of Zimbabwe College of Health Sciences, Harare, Zimbabwe.
Blessmore Vimbai ChaibvaMinistry of Health and Child Care, Harare, Zimbabwe.
Ioana D OlaruLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Nyasha MasukaZimbabwe College of Public Health Physicians, Harare, Zimbabwe.
Janney WaleIndependent Consumer Advocate, Brunswick, VIC, Australia.
Lenias HwendaMedicines for Africa, Johannesburg, South Africa.
Regina KamogaUganda Alliance of Patients' Organizations (UAPO), Kampala, Uganda.
Ruaraidh HillLiverpool Reviews and Implementation Group, University of Liverpool, Liverpool, United Kingdom.
Corrado BarbuiWHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Section of Psychiatry, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Tomasz BochenekDepartment of Nutrition and Drug Research, Faculty of Health Sciences, Jagiellonian University Medical College, Krakow, Poland.
Amanj KurdiStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Stephen CampbellCentre for Primary Care, Division of Population Health, Health Services Research and Primary Care, University of Manchester, Manchester, United Kingdom.
Antony P MartinFaculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.
Thuy Nguyen Thi PhuongPharmaceutical Administration & PharmacoEconomics, Hanoi University of Pharmacy, Hanoi, Vietnam.
Binh Nguyen ThanhPharmaceutical Administration & PharmacoEconomics, Hanoi University of Pharmacy, Hanoi, Vietnam.
Brian GodmanSchool of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Sefako Makgatho Health Sciences University · ZAUniversity of Bamenda · CMUniversity of Botswana · BWUniversity of Nairobi · KEUniversity of Namibia · NAUniversity of Pretoria · ZAChildren Cancer Hospital · EGHanoi University of Pharmacy · VNSouthern Africa Nazarene University · SZSteve Biko Hospital · ZAUniversity of Ghana · GHUniversity of Malawi · MWUniversity of Zambia · ZM37 Military Hospital · GHCommunity Health And Information Network · UGEgerton University · KEEkiti State University · NGElement Six (United Kingdom) · GBFederal Ministry of Health · SDGhana Health Service · GH

Funding

Medical Research Council MC_PC_16090
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has already claimed considerable lives. There are major concerns in Africa due to existing high prevalence rates for both infectious and non-infectious diseases and limited resources in terms of personnel, beds and equipment. Alongside this, concerns that lockdown and other measures will have on prevention and management of other infectious diseases and non-communicable diseases (NCDs). NCDs are an increasing issue with rising morbidity and mortality rates. The World Health Organization (WHO) warns that a lack of nets and treatment could result in up to 18 million additional cases of malaria and up to 30,000 additional deaths in sub-Saharan Africa.

objectiveDocument current prevalence and mortality rates from COVID-19 alongside economic and other measures to reduce its spread and impact across Africa. In addition, suggested ways forward among all key stakeholder groups. OUR APPROACH: Contextualise the findings from a wide range of publications including internet-based publications coupled with input from senior-level personnel. ONGOING ACTIVITIES: Prevalence and mortality rates are currently lower in Africa than among several Western countries and the USA. This could be due to a number of factors including early instigation of lockdown and border closures, the younger age of the population, lack of robust reporting systems and as yet unidentified genetic and other factors. Innovation is accelerating to address concerns with available equipment. There are ongoing steps to address the level of misinformation and its consequences including fines. There are also ongoing initiatives across Africa to start addressing the unintended consequences of COVID-19 activities including lockdown measures and their impact on NCDs including the likely rise in mental health disorders, exacerbated by increasing stigma associated with COVID-19. Strategies include extending prescription lengths, telemedicine and encouraging vaccination. However, these need to be accelerated to prevent increased morbidity and mortality.

conclusionThere are multiple activities across Africa to reduce the spread of COVID-19 and address misinformation, which can have catastrophic consequences, assisted by the WHO and others, which appear to be working in a number of countries. Research is ongoing to clarify the unintended consequences given ongoing concerns to guide future activities. Countries are learning from each other.

Indexed as

AfricaCOVID-19health policymisinformationprevalencereviewtreatmentunintended consequences

Identifiers

PMID33071775
PMCPMC7533592
OpenAlexW3048223582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.