Evidence map›Paper›PMID 33071732›Full record

ArticleFrontiers in neuroscience2020

Instantaneous Cardiac Baroreflex Sensitivity: xBRS Method Quantifies Heart Rate Blood Pressure Variability Ratio at Rest and During Slow Breathing.

Niels Wessel, Andrej Gapelyuk, Jonas Weiß, Martin Schmidt, Jan F Kraemer, Karsten Berg, Hagen Malberg, Holger Stepan, Jürgen Kurths

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. On the accuracy of sequence methods for baroreflex sensitivity estimation.Physical and engineering sciences in medicine · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Niels WesselDepartment of Physics, Humboldt-Universität zu Berlin, Berlin, Germany.
Andrej GapelyukDepartment of Physics, Humboldt-Universität zu Berlin, Berlin, Germany.
Jonas WeißInstitute of Biomedical Engineering, Technische Universität Dresden, Dresden, Germany.
Martin SchmidtInstitute of Biomedical Engineering, Technische Universität Dresden, Dresden, Germany.
Jan F KraemerDepartment of Physics, Humboldt-Universität zu Berlin, Berlin, Germany.
Karsten BergDepartment of Physics, Humboldt-Universität zu Berlin, Berlin, Germany.
Hagen MalbergInstitute of Biomedical Engineering, Technische Universität Dresden, Dresden, Germany.
Holger StepanDivision of Obstetrics, Universitätsklinikum Leipzig, Leipzig, Germany.
Jürgen KurthsDepartment of Physics, Humboldt-Universität zu Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous baroreflex sensitivity (BRS) is a widely used tool for the quantification of the cardiovascular regulation. Numerous groups use the xBRS method, which calculates the cross-correlation between the systolic beat-to-beat blood pressure and the R-R interval (resampled at 1 Hz) in a 10 s sliding window, with 0-5 s delays for the interval. The delay with the highest correlation is selected and, if significant, the quotient of the standard deviations of the R-R intervals and the systolic blood pressures is recorded as the corresponding xBRS value. In this paper we test the hypothesis that the xBRS method quantifies the causal interactions of spontaneous BRS from non-invasive measurements at rest. We use the term spontaneous BRS in the sense of the sensitivity curve is calculated from non-interventional, i.e., spontaneous, baroreceptor activity. This study includes retrospective analysis of 1828 measurements containing ECG as well as continues blood pressure under resting conditions. Our results show a high correlation between the heart rate - systolic blood pressure variability (HRV/BPV) quotient and the xBRS (

Indexed as

barorecepter reflex sensitivityblood pressure variabilityheart rate variabilityrestslow breathing

Identifiers

PMID33071732
PMCPMC7543095

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.