ArticleFrontiers in neuroscience2020
Gender-Specific Risk Factors and Comorbidities of Bothersome Tinnitus.
Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Low Evidence for Tinnitus Risk Factors: A Systematic Review and Meta-analysis.Journal of the Association for Research in Otolaryngology : JARO · 2023Pooled it
- The Association Between Effectiveness of Tinnitus Intervention and Cognitive Function-A Systematic Review.Frontiers in psychology · 2020Pooled it
- Periodontal Procedure Intensity and Incident Tinnitus in Korean Adults: A Nationwide Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Tinnitus and tinnitus disorder: Genetic, neurobiological, and clinical differentiation.iScience · 2026Review
- Tinnitus is not associated with cardiovascular risk factors or mortality in the Gutenberg Health Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Psychosocial Work Stress, Resilience and the Risk of Tinnitus-Results from a Population-Based Cohort Study.Medicina (Kaunas, Lithuania) · 2025Observational
- Does the Patient's Sex Have an Impact on Beneficial Effects ofJournal of clinical medicine · 2025Article
- Causal Effects Between Anxiety-Depressive and Subjective Tinnitus in Europe: A Bidirectional Mendelian Randomization Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Mourning for Silence: Bereavement and Tinnitus-A Perspective.Journal of clinical medicine · 2025Article
- Sensory processing in medically unexplained pain syndrome. A systematic review.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
- Correlation of non-auditory comorbidities and hearing loss in chronic subjective tinnitus patients: a retrospective database study.Frontiers in neurology · 2025Article
- Tinnitus and cardiovascular disease: the population-based Tromsø Study (2015-2016).BMJ public health · 2024Article
- Clinical and audiological characteristics in adults with tinnitus in South Africa.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2024Article
- Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024Review
- Depression, anxiety and brain volume after hearing loss and tinnitus: cohort study in the UK Biobank.BJPsych open · 2024Article
- The impact of tinnitus on Dutch general practices: A retrospective study using routine healthcare data.PloS one · 2024Article
- Aging Makes the Heart Grow Fonder: Age Influences Hearing Ability and Interactions between Psychological Phenomena in Patients with Chronic Tinnitus.Journal of personalized medicine · 2023Article
- [Analysis of items on the short forms of the tinnitus questionnaire: Mini-TQ-12 and Mini-TQ-15].HNO · 2023Article
- Tinnitus and Influencing Comorbidities.Laryngo- rhino- otologie · 2023Review
- Prediction Models for Tinnitus Presence and the Impact of Tinnitus on Daily Life: A Systematic Review.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims to identify gender-specific risk factors associated with the presence of bothersome tinnitus (compared with non-bothersome tinnitus), including sociodemographic and lifestyle factors, tinnitus-associated phenomena (hearing loss, traumatic experiences, sleep disturbances), and physical as well as mental comorbidities.
methodsWe conducted a cross-sectional study using survey data from the Swedish LifeGene cohort containing information on self-reported tinnitus (
results(1) The majority of factors that differed in frequencies between bothersome and non-bothersome tinnitus were equal for both genders. Women with bothersome tinnitus specifically reported higher rates of cardiovascular disease, thyroid disease, epilepsy, fibromyalgia, and burnout, and men with bothersome tinnitus reported higher rates of alcohol consumption, Ménière's disease, anxiety syndrome, and panic (compared with non-bothersome tinnitus, respectively). (2) Across both genders, multivariate logistic regression analyses revealed significant associations between bothersome tinnitus and age, reduced hearing ability, hearing-related difficulties in social situations, and reduced sleep quality. In women, bothersome tinnitus was specifically associated with cardiovascular disease and epilepsy; in men, with lower education levels and anxiety syndrome. (3) Moderated logistic regression analyses revealed that the effects of low education and anxiety syndrome were present in men, but not in women, whereas the effects of age, reduced hearing ability and related difficulties, cardiovascular disease, epilepsy, and burnout were not gender specific.
conclusionIrrespective of gender, bothersome tinnitus is associated with higher age, reduced hearing ability, hearing-related difficulties, cardiovascular disease, epilepsy, and burnout. Gender-specific effects comprise low levels of education and the presence of anxiety syndrome for men. These findings need to be interpreted with caution, yet they suggest the presence of gender-specific biopsychosocial influences in the emergence or maintenance of bothersome tinnitus. Future studies ought to investigate the underlying mechanisms of the observed relationships.
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