OROFACIAL CLEFTS AND CARDIOVASCULAR RISK AND DISEASES: THE CAUSAL RELATIONSHIP AND ASSOCIATIONS.

C E Nwaze, O Adebayo, A M Adeoye, V Akinmoladun

Abstract read

In one paragraph

Article in Annals of Ibadan postgraduate medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Leveraging the genetics of human face shape boosts the discovery of orofacial cleft risk loci.medRxiv : the preprint server for health sciences · 2026
Article
Undernutrition in young children with congenital heart disease undergoing cardiac surgery in a low-income environment.BMC pediatrics · 2024
Observational
Spectrum of congenital heart disease in Nepal from 2002-2022: A systematic review and meta-analysis.Health science reports · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

C E NwazeCollege of Medicine, University of Ibadan, Ibadan.

O AdebayoDepartment of Medicine, University College Hospital, Ibadan.

A M AdeoyeDepartment of Medicine, University of Ibadan/University College Hospital, Ibadan.

V AkinmoladunDepartment of Oral and Maxillofacial Surgery, University of Ibadan/University College Hospital, Ibadan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a complex interplay between orofacial clefts (OFCs) or cleft of the lip and palate and cardiovascular risk factors and cardiac diseases. The presence of maternal cardiovascular risk factors serves as a potent predisposing factor to the development of OFCs during foetal development in addition to the fact that various congenital anomalies are associated with OFCs either in syndromic or non-syndrome relationship. This article narratively explores this complex interplay, which is not uncommon.

Indexed as

Cardiovascular diseasesCleft lip and palateHypertensionNatalObesityPrenatal

Identifiers

PMID33071693

PMCPMC7513382

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.