ArticleReproductive medicine and biology2020
The impact of endometrial injury on reproductive outcomes: results of an updated meta-analysis.
Article in Reproductive medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Optimal timing to transfer embryos for women who underwent hysteroscopy: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Effects of Nonablative Er-YAG Laser on Human Endometrial Stromal Cells (hESCs): A Pilot Study.Lasers in surgery and medicine · 2025Article
- Endometrial scratching before euploid embryo transfer: a case-control study.Journal of assisted reproduction and genetics · 2025Article
- Endometrial scratching and intralipid treatment-no general recommendations.Frontiers in reproductive health · 2024Article
- Good practice recommendations on add-ons in reproductive medicine†.Human reproduction (Oxford, England) · 2023Article
- Endometrial scratching during hysteroscopy in women undergoingFrontiers in surgery · 2023Review
- Comparing the effects of endometrial injury in the luteal phase and follicular phase onFrontiers in endocrinology · 2022Article
- The impact of endometrial injury on reproductive outcomes: results of an updated meta-analysis.Reproductive medicine and biology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is still unclear whether endometrial injury (EI) has a beneficial effect on reproductive outcomes, and if so, the optimal procedure characteristics are not clear. All previous papers concluded that more research is needed, and as additional studies were recently published, the insights on EI have changed significantly.
methodsSearches were conducted in MEDLINE, Embase, Web of Science, and Cochrane Library, to identify randomized controlled trials examining the EI effect on IVF outcomes in women at least one previous failed cycle.
results2015 references were identified through database searching. Ultimately, 17 studies were included, involving 3016 patients. Clinical pregnancy rate (CPR) (RR = 1.19, [95% CI 1.06-1.32],
conclusionAccording to the present meta-analysis, EI may be offered to younger patients with few previous failed cycles and should be additionally studied in an RCT comparing different timing and more than one EI before treatment.
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Registered trials
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