Evidence map›Paper›PMID 33071557›Full record

ArticleBiochemia medica2020

Urine neutrophil gelatinase-associated lipocalin concentration in healthy newborns during the first three postnatal days.

Vinka Mikulić, Dunja Rogić, Ivanka Mikulić, Kristina Ljubić, Ana Ćuk, Vajdana Tomić, Helena Radić Mišković

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemia medica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Vinka MikulićDepartment of Laboratory Diagnostics, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.
Dunja RogićDepartment of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, Croatia.
Ivanka MikulićDepartment of Laboratory Diagnostics, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.
Kristina LjubićDepartment of Laboratory Diagnostics, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.
Ana ĆukDepartment of Laboratory Diagnostics, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.
Vajdana TomićDepartment of Obstetrics and Gynaecology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.
Helena Radić MiškovićDepartment of Neonatology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.
University Clinical Hospital Mostar · BAUniversity Hospital Centre Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUrine neutrophil gelatinase-associated lipocalin (uNGAL) is a biochemical marker significant for early prediction of acute kidney injury in adults. However, it has not been examined sufficiently among the infant population, particularly newborns in terms of reference values. The aim of our study was to determine the concentration of uNGAL in healthy term newborns and to determine if there was a difference in uNGAL concentration according to gender, postnatal age and birth weight. MATERIALS AND

methodsOur study involved 81 healthy term newborns birth (≥ 37 weeks, Apgar score ≥ 8 in the first minute after birth, CRP < 5 mg/L). Urine NGAL was measured using chemiluminescent microparticle immunoassay (CMIA) within 72 hours after birth, on Architect plus ci8200 analyser (Abbott, Chicago, USA). Data were analysed using Statistica software.

resultsThe median concentration of uNGAL in the whole study group of healthy term newborns was 27.1 ng/mL (16.5-56.0 ng/mL) (newborn girls, 27.1 ng/mL (15.8-47.9 ng/mL); newborn boys, 27.9 ng/mL (16.5-61.0 ng/mL), P = 0.941). Median uNGAL concentration according to postnatal age expressed in days was 28.2 ng/mL (11.7-57.2 ng/mL) 1

conclusionsThere were no significant difference in uNGAL concentration in relation to gender, postnatal age and birth weight.

Indexed as

Acute Kidney InjuryBirth WeightC-Reactive ProteinFemaleHumansImmunoassayInfant, NewbornLipocalin-2Luminescent MeasurementsMalePostnatal CareReagent Kits, DiagnosticC-Reactive ProteinLipocalin-2Reagent Kits, Diagnostichealthy term newbornsneutrophil gelatinase-associated lipocalinurine

Identifiers

PMID33071557
PMCPMC7528642
OpenAlexW3092769043

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.