Evidence map›Paper›PMID 33071468›Full record

ReviewNeurology, psychiatry, and brain research2020

Seizure and COVID-19: Association and review of potential mechanism.

Naureen Narula, Rudman Joseph, Nakul Katyal, Aref Daouk, Sudeep Acharya, Akshay Avula, Rabih Maroun

Open access · greenAbstract readReview
In one paragraph

Review in Neurology, psychiatry, and brain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Impact of Omicron Wave on Pediatric Febrile Seizure.Journal of Korean medical science · 2023
    Article
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  11. Review
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  13. Article
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  16. Review
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Naureen NarulaDepartment of Pulmonary and Critical Care Medicine, Northwell Health- Staten Island University Hospital, Staten Island, NY, USA.
Rudman JosephDepartment of Internal Medicine, Northwell Health- Staten Island University Hospital, Staten Island, NY, USA.
Nakul KatyalDepartment of Neurology, University of Missouri, Columbia, MO, USA.
Aref DaoukDepartment of Pulmonary and Critical Care Medicine, Northwell Health- Staten Island University Hospital, Staten Island, NY, USA.
Sudeep AcharyaDepartment of Internal Medicine, Northwell Health- Staten Island University Hospital, Staten Island, NY, USA.
Akshay AvulaDepartment of Internal Medicine, Northwell Health- Staten Island University Hospital, Staten Island, NY, USA.
Rabih MarounDepartment of Pulmonary and Critical Care Medicine, Northwell Health- Staten Island University Hospital, Staten Island, NY, USA.
Northwell Health · USStaten Island University Hospital · USUniversity of Missouri · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, this highly transmissible virus has since spread rapidly around the world. Though respiratory complication is the primarily reported manifestation though rare, yet serious neurological complications are being frequently reported in the literature. In selected coronavirus disease-2019 (COVID-19) cases neurologic complications may manifest as seizures. In this paper, we have reviewed current literature on seizures linked with SARS- COV 2 infection including published or pre-print original articles, review articles, and case reports. We have discussed the electroencephalogram (EEG), imaging, and Cerebrospinal fluid (CSF) findings in patients with COVID-19 presenting with seizure. We will be concluding the paper by briefly discussing the three mechanisms by which seizures can develop in patients infected with SARS- COV 2 - (a) Direct Mechanism (b) Indirect Mechanism and (c) Exacerbation of Seizure in Patients with Epilepsy (PWE). Our aim is to update the physicians working with COVID-19 patients about this potential complication and hope that understanding of these proposed mechanisms can provide an opportunity for the physicians for early diagnosis or even better, help prevent this complication.

Indexed as

BrainCentral nervous systemCOVID-19NeuroscienceSARS-Cov-2Seizure

Identifiers

PMID33071468
PMCPMC7553058
OpenAlexW3092700060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.