ArticleGut and liver2021
A Nationwide Cohort Study Shows a Sex-Dependent Change in the Trend of Peptic Ulcer Bleeding Incidence in Korea between 2006 and 2015.
Article in Gut and liver, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Sex as a Biological Factor in the Changes in Disease Patients During Ramadan Intermittent Fasting: A Systematic Review.Frontiers in nutrition · 2022Pooled it
- Management of Peptic Ulcer Disease in Patients Taking Antithrombotic Agents.The Korean journal of helicobacter and upper gastrointestinal research · 2026Review
- Trends and inequities in peptic ulcer mortality across the United States, 1999-2023.BMC gastroenterology · 2026Article
- Clinical evaluation of laparoscopic repair with quadruple therapy for acute gastric ulcer perforation in elderly patients.Frontiers in pharmacology · 2026Article
- Analysis of risk factors for bleeding after gastric endoscopic submucosal dissection with an emphasis on age and sex differences: A nationwide population-based study.Surgical endoscopy · 2025Article
- Changing Epidemiology and Etiology of Upper Gastrointestinal Bleeding.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- Association between menopause, postmenopausal hormone therapy and peptic ulcer disease in Taiwanese population.Scientific reports · 2025Article
- [Emerging Diagnostic Techniques and Therapies for Upper Gastrointestinal Bleeding].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- Peptic Ulcer Disease.The Korean journal of helicobacter and upper gastrointestinal research · 2025Review
- Mortality Risk Scoring System in Patients after Bleeding from Cancers in the Upper Gastrointestinal Tract.Gut and liver · 2024Article
- [Non-Variceal Upper Gastrointestinal Bleeding].The Korean journal of helicobacter and upper gastrointestinal research · 2024Review
- Changing trends and characteristics of peptic ulcer disease: A multicenter study from 2010 to 2019 in Korea.World journal of gastroenterology · 2023Article
- Upper and Lower Gastrointestinal Bleeding: A Retrospective Study on 10 Years Experiences in Southeastern Iran.Middle East journal of digestive diseases · 2023Article
- Efficacy of Tranexamic Acid in the Treatment of Massive Upper Gastrointestinal Bleeding: A Randomized Clinical Trial.Cureus · 2023Article
- Socioeconomic Disparities: A Possible Clue to a Puzzle Encompassing Organic to Functional Gastrointestinal Disorders.Journal of neurogastroenterology and motility · 2022Article
- Role of the antioxidant pathway in the healing of peptic ulcers induced by ischemia-reperfusion in male and female rats treated with Eugenia punicifolia.Inflammopharmacology · 2022Article
- [How to Study the Sex and Gender Effect in Biomedical Research?]The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/Aims: The incidence of peptic ulcer disease has decreased in past decades; however, the trends in peptic ulcer bleeding (PUB) are inconsistent among regions. This study aimed to investigate the trends in PUB incidence and the effect of risk factors on PUB in Korea. Methods: The records of patients hospitalized with PUB from 2006 to 2015 were retrieved from the Korean National Health Insurance Service Database. Standardized incidences of PUB were calculated, and the clinical characteristics such as age, sex, Results: In total, 151,507 hospitalizations with PUB were identified. The overall annual hospitalization rate was 34.98 per 100,000 person-years. The incidence of PUB showed no significant change from 2006 to 2008 and decreased from 2008 to 2015, with an annual change of -2.7% (p<0.05); however, this change was only significant in men. The incidence of PUB was higher in men than in women between 40 and 70 years old and higher in women than in men older than 80 years. From 2006 to 2015, the Conclusions: Over the past decade, the incidence of PUB has decreased in a sex-specific manner. There has been a decreasing trend in the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.