Evidence map›Paper›PMID 33070999›Full record

ReviewVaccine2020

Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) standardized template for collection of key information for benefit-risk assessment of live-attenuated viral vaccines.

Marc Gurwith, Richard C Condit, Jean-Louis Excler, James S Robertson, Denny Kim, Patricia E Fast, Stephen Drew, David Wood, Bettina Klug, Mike Whelan and 6 more

Abstract readReview
In one paragraph

Review in Vaccine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Marc GurwithBrighton Collaboration, A Program of the Task Force for Global Health, Decatur, GA, USA.
Richard C ConditDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, USA.
Jean-Louis ExclerInternational Vaccine Institute, Seoul, Republic of Korea.
James S RobertsonIndependent Adviser, United Kingdom.
Denny KimJanssen Pharmaceuticals, Titusville, NJ, USA.
Patricia E FastInternational AIDS Vaccine Initiative, New York, NY, USA; Stanford School of Medicine, Paolo Alto, CA, USA.
Stephen DrewIndependent Adviser, USA.
David WoodIndependent Adviser, United Kingdom.
Bettina KlugPaul-Ehrlich-Institut, Federal Institute for Vaccines and Biomedicines, Langen, Germany.
Mike WhelanProject Leader, CEPI, UK.
Tamala Mallett MooreSanofi Pasteur, Swiftwater, PA, USA.
Najwa Khuri-BulosUniversity of Jordan, Amman, Jordan.
Emily R SmithBrighton Collaboration, A Program of the Task Force for Global Health, Decatur, GA, USA. Electronic address: bc-coordinator@taskforce.org.
Robert T ChenBrighton Collaboration, A Program of the Task Force for Global Health, Decatur, GA, USA.
Sonali KochharGlobal Healthcare Consulting, New Delhi, India; University of Washington, Seattle, WA, USA.
Brighton Collaboration Viral Vector Vaccines Safety Working Group V3SWG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several live-attenuated viral vaccine candidates are among the COVID-19 vaccines in development. The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) has prepared a standardized template to describe the key considerations for the benefit-risk assessment of live-attenuated viral vaccines. This will help key stakeholders assess potential safety issues and understand the benefit-risk of such vaccines. The standardized and structured assessment provided by the template would also help to contribute to improved communication and support public acceptance of licensed live-attenuated viral vaccines.

Indexed as

COVID-19 VaccinesDrug Evaluation, PreclinicalHumansRisk AssessmentSocieties, ScientificVaccines, AttenuatedViral VaccinesCOVID-19 VaccinesVaccines, AttenuatedViral VaccinesAttenuatedBenefit-riskBrighton CollaborationCEPICOVID-19LiveSafetyTemplateVaccineViral

Identifiers

PMID33070999
PMCPMC7563577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.